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Long-term Results of Catheter Ablation for Irregular and Fast Heart Rhythms

Follows adults with atrial fibrillation or ventricular tachycardia treated with catheter ablation procedures.

Key facts

Who runs it
Beijing Anzhen Hospital
Where
Beijing, ChinaSee the 2 sites
Trial code
Registry title
Complex Arrhythmia Registry
Status
Recruiting
People taking part
4,000 people, planned
Started
21 Oct 2025
Expected to end
Jun 2032
Type of study
Observational, 3 groups
Treatments tested
  • AF ablation
  • VT ablation
Record updated
4 June 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who will have catheter ablation for the first time, for atrial fibrillation (AF) or for ventricular tachycardia (VT) linked to a heart disease. The ablation must use a 3D mapping system.

Age
18 years or older
Sex
All sexes can join.
Disease stage
AF group: paroxysmal or persistent AF. VT group: VT linked to structural heart disease, such as ischemic heart disease or cardiomyopathy (DCM, ARVC, HCM).
Earlier treatment
The planned ablation must be the first catheter ablation for AF or for VT.

Main reasons for not taking part

  • AF caused by a clearly reversible cause (for example hyperthyroidism or acute alcohol intoxication)
  • VT caused by a temporary or reversible cause, or VT without structural heart disease
  • Unstable angina or heart attack within 30 days (AF group); heart surgery within 60 days (VT group)
  • Severe active infection such as sepsis or septic shock
  • Joining another interventional trial that could affect the results

The registry criteria, word for word

Show all 2 criteriaShow less

Other criteria

  • Atrial Fibrillation (AF) Cohort:; Inclusion Criteria (Patients must meet ALL of the following criteria):; Age ≥ 18 years; Diagnosed with atrial fibrillation (AF), including paroxysmal AF (PAF) and persistent AF (PsAF); Scheduled to undergo first-time catheter ablation for AF; Procedure to be performed using a 3D mapping system; Provision of signed written informed consent for study participation and willingness and ability to comply with all protocol-required follow-up assessments; Exclusion Criteria (Patients meeting ANY of the following criteria will be excluded):; Severe congenital heart disease (e.g., Tetralogy of Fallot, corrected transposition of the great arteries); AF secondary to a clearly reversible cause (e.g., hyperthyroidism, post-operative state, acute alcohol intoxication); Unstable angina pectoris or acute myocardial infarction (MI) within 30 days prior to enrollment/procedure; Severe active infection (e.g., septic shock, sepsis); Contraindications to anticoagulation therapy; Current participation in another interventional clinical trial that may confound the results of this study; Any other condition where, in the investigator's judgment, the patient is unsuitable for participation in this study
  • Ventricular Tachycardia (VT) Cohort; Inclusion Criteria (Patients must meet ALL of the following criteria):; Age ≥ 18 years; Diagnosed with ventricular tachycardia (VT) associated with underlying structural heart disease, including:; Ischemic heart disease (e.g., prior MI, coronary artery disease); Non-ischemic cardiomyopathy (e.g., dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), hypertrophic cardiomyopathy (HCM)); Scheduled to undergo first-time catheter ablation for VT; Procedure to be performed using a 3D mapping system; Provision of signed written informed consent for study participation and willingness and ability to comply with all protocol-required follow-up assessments; Exclusion Criteria (Patients meeting ANY of the following criteria will be excluded):; VT due to a transient or reversible cause (e.g., acute myocardial ischemia, severe electrolyte imbalance); Idiopathic ventricular tachycardia (VT occurring in the absence of structural heart disease); Cardiac surgery within 60 days prior to the planned ablation procedure; Severe coagulopathy (e.g., platelet count < 50 x 10⁹/L, disseminated intravascular coagulation (DIC)); Severe heart failure with left ventricular ejection fraction (LVEF) < 20%; Severe active infection (e.g., septic shock, sepsis); Current participation in another interventional clinical trial that may confound the results of this study; Any other condition where, in the investigator's judgment, the patient is unsuitable for participation in this study

Where in China

  • Beijing Anzhen Hospital, Capital Medical UniversityBeijing, ChinaContact: Jing LinNot yet recruiting
  • No. 2 Anzhen Rd, Chaoyang District, 100029Beijing, ChinaContact: Deyong Long, MDTaking people

About the trial

What the trial wants to find out

This is a prospective, non-randomized, multicenter observational registry study designed to systematically evaluate the long-term efficacy and safety of catheter ablation for treating atrial fibrillation (AF) and ventricular tachycardia (VT) in Chinese patients.

The 3 groups in the trial

  • PAF

    Paroxysmal atrial fibrillation

    Treatment: AF ablation

  • PeAF

    Persistent atrial fibrillation

    Treatment: AF ablation

  • VT

    Ventricular tachycardia

    Treatment: VT ablation

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Complex Arrhythmia Registry(CAR): Long-term Outcomes of Catheter Ablation for Atrial Fibrillation or Ventricular Tachycardia: A Multicenter, Prospective Cohort Study
Plain-language title
Long-term Results of Catheter Ablation for Irregular and Fast Heart RhythmsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
4 June 2026