Changes in Etomidate Dosage in Patients With Insomnia Undergoing Intravenous Anesthesia
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- Are you between 18 and 64 years old?
Source: NCT07028177, who can take part
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- Who runs it
- Beijing Tiantan Hospital
- Trial code
- NCT07028177
- Record updated
- 22 July 2026
- Original description
To compare the dosage requirement of etomidate under intravenous anesthesia between patients with insomnia and those with normal sleep pattern.Read full original descriptionShow less
Changes in Etomidate Dosage in Patients With Insomnia Undergoing Intravenous Anesthesia: a Prospective Cohort Study
To compare the dosage requirement of etomidate under intravenous anesthesia between patients with insomnia and those with normal sleep pattern.
Inclusion: Patients with insomnia:; Age of 18 - 64 years; American Society of Anesthesiologists (ASA) physical status of I - II; Body mass index (BMI) of 15 - 30; Patients undergoing elective thoracoscopy, laparoscopy, hysteroscopy, open abdominal surgery, open thoracic surgery, open spinal surgery, craniotomy surgery, and digestive endoscopy under general anesthesia; Positive screening results according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for insomnia disorder; 8-item Sleep Condition Indicator (SCI; score 0-4; range 0-32, higher score means better sleep) scored 16 or less; Patients with normal sleep:; Age of 18 - 64 years; ASA physical status of I - II; BMI of 15 - 30; Patients undergoing elective thoracoscopy, laparoscopy, hysteroscopy, open abdominal surgery, open thoracic surgery, open spinal surgery, craniotomy surgery, and digestive endoscopy under general anesthesia; No history or evidence of insomnia.
Exclusion: Any contraindication to intravenous anesthetic drug, such as hypotension or shock; Associated with any neurological disease; History of allergy to any drug used in the study; Patients with sleep apnea syndrome; acute upper respiratory infection; Patients with psychological diseases who report suicidal thoughts; Daily alcohol consumption; Pregnancy or breastfeeding; Patients who need to work or take care of children/elderly people frequently at night.