Blood Test sST2 Tracked in Children Having Heart Defect Surgery
Measures a blood marker, sST2, in children under 18 before and after heart surgery.
Plain-language title generated from the registry record
Registry title: Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.
Key facts
- Where
- Zurich, SwitzerlandSee the site
Where in Switzerland
- University Children's Hospital ZurirchZurich, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Martin Schweiger
- Trial code
- NCT07029230
- Record updated
- 17 November 2025
- Original description
Patients younger than 18 scheduled for congenital heart surgery will be assessed during and post-operatively as well as at the first follow-up after 9-12 month for the novel biomarker sST2. We will assess the marker independently and in evaluation with other blood biomarkers to evaluate sings of heart failure. Compared to established biomarkers, sST2 promises thereby to be less variable to factors like age or acute kidney injury, rendering it potentially more reliable in the field of congenital cardiac surgery.Read full original descriptionShow less
Biomarker in Congenital Cardiac Surgery - sST2 Marker in Heart Failure in Congenital Heart Disease After Surgery Research and Translational Study
Patients younger than 18 scheduled for congenital heart surgery will be assessed during and post-operatively as well as at the first follow-up after 9-12 month for the novel biomarker sST2. We will assess the marker independently and in evaluation with other blood biomarkers to evaluate sings of heart failure. Compared to established biomarkers, sST2 promises thereby to be less variable to factors like age or acute kidney injury, rendering it potentially more reliable in the field of congenital cardiac surgery.
Inclusion: Consented for cardiopulmonary bypass surgery for cardiac reason; Conversational skills in German (by child and/or representative) to be able to fully understand and sign a written consent in German language.
Exclusion: Body weight at time of surgery less than 2.5 kg; Know genetic life limiting conditions; Syndrome patients who are scheduled or highly likely to be operated on more than one organ; Being recruited and enrolled for an interventional study protocol.