Laser acupoint treatment for dry mouth in head and neck cancer patients
Tests laser acupoint stimulation for dry mouth during chemoradiation in head and neck cancer.
Key facts
- Who runs it
- Cairo University
- Where
- Cairo, EgyptSee the site
- Trial code
- Registry title
- Laser Acupoints Stimulation on Xerostomia Related Chemoradiotherapy for Head and Neck Cancer Patients
- Status
- Not yet recruiting
- People taking part
- 54 people, planned
- Started
- 18 Jun 2025
- Planned end
- 31 Aug 2025
- Type of study
- Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Medical treatment
- LASER acupoints therapy
- Pseudo-LASER acupoints therapy
- Record updated
- 19 June 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 40 to 70 with head and neck cancer (nasopharyngeal carcinoma) who are having chemoradiation therapy. It tests laser acupoint stimulation for dry mouth.
- Age
- 40 Years to 70 Years
- Sex
- All sexes can join.
- Disease stage
- Carcinoma in the head and neck area (NPC), treated with chemoradiation therapy. Parotid and submandibular glands must be anatomically intact.
- Earlier treatment
- Must not have taken any drug or herbal medicine in the past 30 days that could affect salivary function.
Main reasons for not taking part
- History of xerostomia (dry mouth)
- Suspected or confirmed physical closure of the salivary gland ducts on either side
- Known bleeding disorders, or taking heparin or warfarin
- Contraindications for acupuncture at any acupoints
- History of cerebrovascular accident or spinal cord injury
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Chemoradiation therapy
- Carcinoma in the head and neck area (NPC)
- Anatomically intact parotid and submandibular glands
- All patients will be clinically and medically stable when attending the study
Who cannot take part
- They had taken any drug or herbal medicine in the past 30 days that could affect salivary function
- Any therapy that may affect treatment
- They had a history of xerostomia
- They had known bleeding disorders
- They had history of cerebrovascular accident or spinal cord injury
- They had suspected or confirmed physical closure of salivary gland
- ducts on either side
- They Were taking heparin or warfarin
- They had contraindications for the use of acupuncture at any acupoints
- They were planning to, or ended up taking such a substance during the study
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 70 years old?
Where in Egypt
- El Hussein university HospitalCairo, EgyptContact: Nehal Gamal Ebrahim Elwerish, B.ScNo longer taking part
About the trial
What the trial wants to find out
The purpose of the study is to evaluate to effect of LASER acupoints stimulations on xerostomia patients during chemoradiation therapy after head and neck cancer.
The 2 groups in the trial
- LASER acupoints therapy + Medical treatmentTreatment being tested
This group will include twenty-seven patients suffering xerostomia (dryness of mouth), who will receive LASER acupoints therapy (3 times per week, for 4 weeks), plus medical treatment.
Treatment: Medical treatment and LASER acupoints therapy
- Pseudo-LASER acupoints therapy + Medical treatmentPlacebo, for comparison
This group will include twenty-seven patients suffering xerostomia (dryness of mouth), who will receive pseudo-LASER acupoints therapy plus medical treatment (for 4 weeks).
Treatment: Medical treatment and Pseudo-LASER acupoints therapy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Laser Acupoints Stimulation on Xerostomia Related Chemoradiotherapy for Head and Neck Cancer Patients
- Plain-language title
- Laser acupoint treatment for dry mouth in head and neck cancer patientsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07029854, who can take part
- Record updated
- 19 June 2025