Ultrasound Vein Measurement to Predict Low Blood Pressure During Dialysis
Studies an ultrasound vein measurement to predict low blood pressure in dialysis patients.
Plain-language title generated from the registry record
Registry title: Inferior Vena Cava Collapsibility Index and Intradialytic Hypotension
Key facts
- Where
- Wuhu, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with end-stage kidney disease who have had regular hemodialysis for at least three months. It tests an ultrasound measurement of a neck-to-belly vein to predict low blood pressure during dialysis.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- End-stage renal disease (ESRD), on regular hemodialysis for at least three months.
- Earlier treatment
- Regular hemodialysis for at least three months.
Main reasons for not taking part
- Pregnant or breastfeeding women
- Unstable blood pressure or needing drugs to support blood pressure
- Severe heart problems (heart failure NYHA Class III-IV or severe valve disease)
- Blood pressure medicines taken during dialysis sessions
- Cannot have an ultrasound, for example because of severe obesity or wounds
This trial only enrols participants on dialysis. The registry sentence this rests on: Undergoing regular hemodialysis for at least three months.
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07033273, who can take part
Where in China
- The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)Wuhu, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- First Affiliated Hospital of Wannan Medical College
- Trial code
- NCT07033273
- Record updated
- 24 June 2025
- Original description
This multicenter, prospective observational study aims to evaluate the predictive value of the Inferior Vena Cava Collapsibility Index (IVCCI), along with IVC maximum diameter (IVCmax) and IVC minimum diameter (IVCmin), for intradialytic hypotension in patients undergoing maintenance hemodialysis. The study will be conducted at The First Affiliated Hospital of Wannan Medical College, Wuhu City Second People's Hospital, Wuhu Hospital of Chinese Traditional Medicine, Wuhu Jinghu District Hospital, and Wuhu Guangji Hospital. Eligible participants are adults aged 18 years or older with diagnosed end-stage renal disease (ESRD), receiving regular hemodialysis for at least three months. Patients with acute kidney injury, severe cardiac conditions, or other factors likely to influence results will be excluded.Read full original descriptionShow less
The Predictive Value of the Inferior Vena Cava Collapsibility Index for Intradialytic Hypotension: A Prospective Multicenter Observational Stud
This multicenter, prospective observational study aims to evaluate the predictive value of the Inferior Vena Cava Collapsibility Index (IVCCI), along with IVC maximum diameter (IVCmax) and IVC minimum diameter (IVCmin), for intradialytic hypotension in patients undergoing maintenance hemodialysis. The study will be conducted at The First Affiliated Hospital of Wannan Medical College, Wuhu City Second People's Hospital, Wuhu Hospital of Chinese Traditional Medicine, Wuhu Jinghu District Hospital, and Wuhu Guangji Hospital. Eligible participants are adults aged 18 years or older with diagnosed end-stage renal disease (ESRD), receiving regular hemodialysis for at least three months. Patients with acute kidney injury, severe cardiac conditions, or other factors likely to influence results will be excluded.
Ultrasound measurements of IVCCI, IVCmax, and IVCmin will be performed once, precisely at 1 hour after dialysis initiation. IVCmax will be measured during inspiration when the IVC is at its largest, and IVCmin during expiration when it is at its smallest. Blood pressure will be monitored continuously during the procedure. The primary objective is to assess the sensitivity, specificity, and optimal cutoff values of IVCCI, IVCmax, and IVCmin for predicting hypotension, aiming to provide a simple and non-invasive tool to facilitate personalized dialysis management and reduce intradialytic hypotension. A sample size of 188 participants is estimated, with data analyzed using ROC curves and multivariate regression methods. The study protocol adheres to ethical standards and regulatory requirements, demonstrating potential to improve patient safety and treatment outcomes.
Inclusion: Adults aged 18 years or older; Diagnosed with end-stage renal disease (ESRD); Undergoing regular hemodialysis for at least three months.
Exclusion: Use of antihypertensive medications during dialysis sessions; Patients with severe cardiac conditions, including congestive heart failure -classified as NYHA Class III-IV or severe valvular disease; Patients with known allergies to dialysis filters; Pregnant or breastfeeding women; Hemodynamically unstable patients or those requiring vasopressor support; Dialysis sessions terminated for reasons unrelated to hypotension (e.g., technical issues, patient request); Patients who withdraw informed consent during the study; Inability to undergo ultrasound assessment due to factors such as severe obesity or wounds obstructing access.