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Taking people in DenmarkNo phase

Tests a home exercise and support program before heart bypass surgery

Tests a home-based exercise program before bypass surgery in adults with heart disease.

Plain-language title generated from the registry record
Registry title: CABGpreHAB - a Feasibility Study Protocol

Key facts

Where
Copenhagen, DenmarkSee the site

Where in Denmark

  • The Department of Heart and Lung Surgery, Copenhagen University hospital RigshospitaletCopenhagen, DenmarkTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Copenhagen University Hospital, Rigshospitalet
Trial code
NCT07035171
Record updated
29 June 2025
Original description
Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity. These factors, combined with the physiological and psychological stress of surgery, can hinder postoperative recovery. Traditionally, strategies to improve surgical outcomes focus on the intra- and postoperative periods. However, the pre-surgery waiting period offers a "window of opportunity" for prehabilitation, which aims to enhance patients' functional capacity through exercise, nutrition, and psychological support.Read full original descriptionShow less

CABGpreHAB- Home-based Multimodal Prehabilitation (CABGpreHAB) for Elective Patients Awaiting CABG-surgery - a Feasibility Study Protocol

Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity. These factors, combined with the physiological and psychological stress of surgery, can hinder postoperative recovery. Traditionally, strategies to improve surgical outcomes focus on the intra- and postoperative periods. However, the pre-surgery waiting period offers a "window of opportunity" for prehabilitation, which aims to enhance patients' functional capacity through exercise, nutrition, and psychological support.

The CABGpreHAB feasibility study evaluates the feasibility of a home-based multimodal prehabilitation intervention for patients awaiting elective CABG surgery. This randomized pilot study compares the intervention plus usual care to usual care alone, assessing feasibility outcomes like recruitment, retention, attrition, fidelity, and adherence. The study aims to optimize a subsequent full-scale randomized controlled trial (RCT) and improve patient outcomes by leveraging the pre-surgery period for prehabilitation.

Inclusion: Planned to have elective isolated first-time CABG surgery; 18 years or older; Two weeks or more before surgery; Speaks and understands Danish; Gives written informed consent.

Exclusion: Patient with unstable angina pectoris and/ or MI during the last two weeks; Significant ventricular arrhythmia; Severe heart failure, NYHA Class IV; Left ventricular ejection fraction < 35%; Left main stem stenosis >50%; Orthopedic or neurologic preconditions precluding exercise training; Inability to attend the prehabilitation program due to physical limitations; Patients who have cognitive deficits that would disqualify prehabilitation; Lack of capacity to consent.

ClinicalTrials.gov NCT07035171