Taking peopleNo phase
The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
Key facts
- Who runs it
- Ain Shams University
- Where
- Egypt1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Recruiting
- People taking part
- 75 people, planned
- Started
- 8 Mar 2025
- Planned end
- 1 Aug 2025
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Dexamethasone
- NSAIDs
- Control (Standard treatment)
- Record updated
- 25 June 2025
Who can take part
- Age
- 4 years to 10 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Age: Between 4-10 years
- Indications of tonsillectomy such as:; Recurrent acute attacks at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years; Chronic tonsillitis and hypertrophy of tonsils causing sleep apnea, difficulty in deglutition, interference in speech
- Tonsillectomy by cold dissection only
- American Society of Anesthesiologists (ASA) classification 1,2 (Normal Health, Mild systematic disease)
Who cannot take part
- Patients on chronic steroid therapy
- Regular use of analgesics within a week of surgery
- Presence of acute infection in the upper respiratory tract, acute tonsillitis
- American Society of Anesthesiologists (ASA) classification ASA 3,4 (Severe systematic disease such as uncontrolled Diabetes, cardiac disease, liver or kidney disease, life threating medical conditions)
- Hemoglobin level less than 10 gm/dL
- Patients with age less than 4 and more than 10 years
- Indications of tonsillectomy other than chronic tonsillitis such as lymphoma
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 4 and 10 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
The 3 groups in the trial
- 1- First group: will receive local infiltration of steroids (dexamethasone) in tonsillar bed and parTreatment being tested
Treatment: Dexamethasone
- 2- Second group: will receive systemic nonsteroidal anti-inflammatory drugs in the analgesic and antTreatment being tested
2- Second group: will receive systemic nonsteroidal anti-inflammatory drugs in the analgesic and anti-inflammatory dosage and paracetamol.
Treatment: NSAIDs
- 3- Third group: control group will receive NSAIDs, steroids and paracetamol as standard post tonsillExisting treatment, for comparison
Treatment: Control (Standard treatment)
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain: A Prospective Randomized Controlled Study.
- Fit questions
- Built from NCT07035314, who can take part
- Record updated
- 25 June 2025