Studying How HPV Spreads Between Partners and Within Families
Studies how high-risk HPV spreads between partners and from parents to children.
Plain-language title generated from the registry record
Registry title: Transmission of Oncogenic HPV Infection Among Families
Key facts
- Where
- Kuopio and Tampere, FinlandSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 100 years old?
Source: NCT07036211, who can take part
Where in Finland
- Kuopio University HospitalKuopio, FinlandNo longer taking part
- Tampere University HospitalTampere, FinlandNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tampere University Hospital
- Trial code
- NCT07036211
- Record updated
- 25 June 2025
- Original description
The goal of the Transmission of Oncogenic HPV Infection Among Families (TREVINO) study is to improve understanding of how high-risk human papillomavirus (HPV) infections are transmitted within families. The research focuses on transmission between sexual partners and between parents and children. It also examines how the various microbes may influence the persistence of HPV infections and the development of HPV-related cancers.Read full original descriptionShow less
Transmission of Oncogenic HPV Infection Among Families
The goal of the Transmission of Oncogenic HPV Infection Among Families (TREVINO) study is to improve understanding of how high-risk human papillomavirus (HPV) infections are transmitted within families. The research focuses on transmission between sexual partners and between parents and children. It also examines how the various microbes may influence the persistence of HPV infections and the development of HPV-related cancers.
The study will include up to 300 couples recruited from gynecology and ear, nose, and throat (ENT) clinics in Finland, as well as their children. Participants include individuals with persistent HPV infection, cervical precancer or cancer, or HPV-related head and neck cancer, along with their partners and potentially their offspring.
Participants will provide self-collected samples from the oral and genital areas at multiple time points over up to five years. Questionnaires addressing medical, behavioural, and environmental factors will be completed.
The study is conducted at Tampere University Hospital and Kuopio University Hospital in Finland. Results will inform HPV screening and prevention programs, improve understanding of family-level transmission, and identify potential microbial and genetic markers linked to cancer risk.
Inclusion: Patient with colposcopy clinic detected persisting HR-HPV infection; Patient with diagnosed cervical cancer; Patient with diagnosed OSCC; Patients' sexual partners of women or men that are referred to the colposcopy/gynecological oncology/ENT; offspring (over 12 years old) of the referred couples.
Exclusion: Candidate who don't speak Finnish.