Checks whether women with bladder infection and visible blood need full cancer tests
Studies women 50 and older with bladder infection and visible blood in urine.
Plain-language title generated from the registry record
Registry title: Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
Key facts
- Where
- Uddevalla, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 110 years old?
Source: NCT07037589, who can take part
Where in Sweden
- Uddevalla HospitalUddevalla, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vastra Gotaland Region
- Trial code
- NCT07037589
- Record updated
- 21 November 2025
- Original description
This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.Read full original descriptionShow less
Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed? A Prospective Multicenter Study. BLUSH Trial
This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.
Inclusion: Women ≥50 years of age; Macroscopic hematuria; Presenting for evaluation within the SCP for macroscopic hematuria; Ability to provide informed consent.
Exclusion: Prior diagnosis of bladder cancer, renal cancer, or upper tract urothelial carcinoma (UTUC); Cognitive impairment preventing informed consent; Ongoing or recent treatment for urological malignancy; Serious comorbidities affecting participation or safety; Pregnant women.