Checks whether women with bladder infection and visible blood need full cancer tests
Studies women 50 and older with bladder infection and visible blood in urine.
Plain-language title generated from the registry record
Registry title: Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
Key facts
- Where
- Uddevalla, SwedenSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 50 or older who have visible blood in the urine and are being checked through the urgent suspected-cancer pathway. It studies whether a full cancer check-up is always needed.
- Age
- 50 years or older (the registry lists 18 to 110 years)
- Sex
- Women only
- Disease stage
- Visible (macroscopic) blood in the urine, with acute cystitis (bladder infection) in the study question
- Earlier treatment
- No ongoing or recent treatment for a urological cancer
Main reasons for not taking part
- Earlier diagnosis of bladder cancer, kidney cancer or upper tract urothelial carcinoma (UTUC)
- Memory or thinking problems that prevent giving informed consent
- Ongoing or recent treatment for a urological cancer
- Serious other illnesses that affect taking part or safety
- Pregnancy
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 110 years old?
Source: NCT07037589, who can take part
Where in Sweden
- Uddevalla HospitalUddevalla, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vastra Gotaland Region
- Trial code
- NCT07037589
- Record updated
- 21 November 2025
- Original description
This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.Read full original descriptionShow less
Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed? A Prospective Multicenter Study. BLUSH Trial
This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.
Inclusion: Women ≥50 years of age; Macroscopic hematuria; Presenting for evaluation within the SCP for macroscopic hematuria; Ability to provide informed consent.
Exclusion: Prior diagnosis of bladder cancer, renal cancer, or upper tract urothelial carcinoma (UTUC); Cognitive impairment preventing informed consent; Ongoing or recent treatment for urological malignancy; Serious comorbidities affecting participation or safety; Pregnant women.