Testing MINT conditioning to help walking after stroke
Tests a muscle-signal training method to improve walking in adults after stroke.
Plain-language title generated from the registry record
Registry title: MINT Conditioning to Improve Gait
Key facts
- Where
- Chicago and Dallas, United StatesSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT07041775, who can take part
Where in United States
- Northwestern UniversityChicago, United StatesTaking people
- University of Texas Southwestern Medical CenterDallas, United StatesNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Northwestern University
- Trial code
- NCT07041775
- Record updated
- 8 June 2026
- Original description
This study will test the ability of myoelectric interface for neurorehabilitation (MINT) training to improve walking function.Read full original descriptionShow less
MINT Conditioning to Improve Post-stroke Gait
This study will test the ability of myoelectric interface for neurorehabilitation (MINT) training to improve walking function.
Inclusion: Age at enrollment is 18 to 85; Leg impairment from unilateral stroke at least 6 months prior to screening; Severe to moderate gait impairment (ambulatory with a maximum walking speed of 0.8 m/s, i.e., half of normal speed); Able to stand without assistance; Clinically observable gait asymmetry; Abnormal co-activation between adductor magnus and rectus femoris (R greater than or equal to 0.5).
Exclusion: Cognitive impairment with at least moderately impaired attention on digit-span test, or unable to follow instructions of the MINT task; Visual impairment (such as hemianopia) preventing sufficient perception of the screen to play the games; Anesthesia or severe neglect in the affected leg, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest) that impairs ability to play the games; History of multiple falls within the last year, use of walker for balance, or falling during stance while in the lab in the first session; From the TMS portion of the study only: History of epilepsy in adulthood requiring antiseizure medications; recent/current alcoholism or benzodiazepine/barbiturate abuse or recent history of alcohol/benzodiazepine/barbiturate withdrawal, recent history of cocaine or amphetamine use, skull fractures or skull deficits, concussion within the last 6 months, unexplained recurring headaches, vagus nerve stimulator, cochlear implant, deep brain stimulator, intracranial/carotid stents, cardiac pacemaker/AICD; Participation in another study on the affected leg, or any pharmacological study, within 6 weeks of enrollment; Inability to understand or follow commands in English due to aphasia or other reason that makes it impossible to perform the training; Diffuse or multifocal infarcts; Substantial leg or other pain preventing participation for 60 minutes a day; Spasticity treatment (pharmacological or Botox) on the affected leg within past 3 months; Severe osteoporosis causing hip or other fractures; Contracture limiting the range of motion of the leg; Current pregnancy.