Blood Markers for Tracking Lupus Disease Activity
Tests whether combined blood markers predict lupus activity in adults with lupus.
Plain-language title generated from the registry record
Registry title: AGR+PNI as Predictors of Systemic Lupus Erythematosus Disease Activity
Key facts
- Where
- Sohag, EgyptSee the site
Where in Egypt
- Sohag university hospitalsSohag, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sohag University
- Trial code
- NCT07043153
- Record updated
- 13 May 2026
- Original description
This study aims to evaluate the clinical utility of combining the albumin to globulin ratio (AGR) and the prognostic nutritional index (PNI) as a predictive model for assessing disease activity in patients with systemic lupus erythematosus (SLE). By correlating these nutritional and inflammatory markers with clinical manifestations and laboratory parameters, we hope to establish a simple, non-invasive, and cost-effective tool to aid in monitoring disease activity in Systemic lupus erythematosus patients.Read full original descriptionShow less
Using Combination of Albumin to Globulin Ratio and Prognostic Nutritional Index Model for Predicting Disease Activity in Patients With Systemic Lupus Erythematosus
This study aims to evaluate the clinical utility of combining the albumin to globulin ratio (AGR) and the prognostic nutritional index (PNI) as a predictive model for assessing disease activity in patients with systemic lupus erythematosus (SLE). By correlating these nutritional and inflammatory markers with clinical manifestations and laboratory parameters, we hope to establish a simple, non-invasive, and cost-effective tool to aid in monitoring disease activity in Systemic lupus erythematosus patients.
Inclusion: · Age ≥ 18 years; Both sexes; Patients diagnosed with SLE who fulfilling the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria and matched controls.
Exclusion: Acute infection within the previous four weeks; Co-existing chronic inflammatory or autoimmune diseases; Malignancy; Chronic liver or renal insufficiency; Malignant hematologic diseases; Active hepatitis; Age <18 years; Pregnancy or lactation.