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Taking people in DenmarkPhase 4

NICardipine for Fast Achievement of Systolic BP Targets in ICH

Key facts

Where
Aarhus, DenmarkSee the site
Phase
Phase 4

Where in Denmark

  • Aarhus University HospitalAarhus, DenmarkTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Aarhus University Hospital
Trial code
NCT07044232
Record updated
24 June 2026
Original description
Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP <140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.Read full original descriptionShow less

NICardipine for Fast Achievement of Systolic BP Targets in ICH - a Quasi-randomized, Implementation Trial With Stepwise Rollout of Nicardipin Based Treatment of Hypertension.

Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP <140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.

Inclusion: Age ≥18 years; Acute spontaneous Intracerberal Hemorrhage confirmed by imaging; Symptom onset to stroke center admission <6 hours; Elevated systolic blood pressure (>140 mmHg) at admission.

Exclusion: Presumed fatal bleeding at admission; Secondary causes of ICH (e.g., trauma, vascular malformation); Short remaining life expectancy (<12 month).

ClinicalTrials.gov NCT07044232