Tests a sleep breathing device in people recovering from ischemic stroke
Tests CPAP, a breathing device for sleep apnea, in adults with ischemic stroke.
Plain-language title generated from the registry record
Registry title: Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
Key facts
- Where
- Ribeirão Preto, BrazilSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07044830, who can take part
Where in Brazil
- Hospital das Clínicas, Ribeirão Preto Medical School, University of São PauloRibeirão Preto, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital das Clínicas de Ribeirão Preto
- Trial code
- NCT07044830
- Record updated
- 1 July 2025
- Original description
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.Read full original descriptionShow less
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke - A Randomized Clinical Trial
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
Inclusion: Supratentorial non-lacunar ischemic stroke, including anterior, middle, and posterior cerebral artery territories; Aged 18 to 80 years; Symptom onset or symptom recognition to admission < 12 hours; NIHSS score ≥ 4 and ≤ 20 at enrollment; Signed informed consent form obtained from the participant or their legal representative.
Exclusion: Prior stroke; Previous diagnosis of OSA with current CPAP use or previously failed CPAP; Oxygen therapy >2 L/min; Chronic alcohol or drug use with high risk of withdrawal during hospitalization; Pre-stroke disability (mRS > 1); Clinical instability or severe pre-existing illness (e.g., heart failure, oxygen-dependent COPD, renal or hepatic failure); Known severe neurological disease (e.g., dementia, Parkinson's disease, multiple sclerosis, or other neurodegenerative conditions); Coma or stupor; Orotracheal intubation; Psychomotor agitation; High likelihood of neurosurgical intervention within the first 48 hours; Pregnant or suspected pregnant women; Inability to complete follow-up for any reason; Any contraindication to CPAP use.