Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
Key facts
- Who runs it
- Yuri Semenyuk Rivne Regional Clinical Hospital
- Where
- Ukraine1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 56 people enrolled
- Started
- 7 Jul 2025
- Ended
- 11 Dec 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- ANTERİOR QUADRATUS LUMBORUM BLOCK
- Parenteral administration of analgesics
- General Anesthesia (GA)
- Record updated
- 16 December 2025
Who can take part
- Age
- 40 years to 55 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- patients with ASA status I-II
- patients with symptomatic fibroids
- patients scheduled for abdominl hysterectomy
Who cannot take part
- use of opiate receptor agonists/antagonists before surgery
- uncontrolled hypertension
- refusal to participate in the study at any of its stages
- ASA class ≥ III
- body mass index > 40 kg/m2
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after abdominal hysterectomy and improve quality of recovery after anesthesia. The study hypothesis is that anterior QL block bilaterally before the start of a surgery has no impact on perioperative pain relief, can't reduce the need in opioids and will not improve quality of recovery after anesthesia.
Read full original descriptionShow less
All patients will undergo general anesthesia with tracheal intubation and mechanical ventilation. Patients will be randomized into two groups. In addition to general anesthesia and multimodal analgesia with parenteral medication II (QL) group will receive also anterior quadratus lumborum block as a regional component.
The 2 groups in the trial
- Group I (control)Existing treatment, for comparison
Patients in Group I will undergo general anesthesia with tracheal intubation and mechanical ventilation. Analgesia regimen will include parenteral medication.
Treatment: Parenteral administration of analgesics and General Anesthesia (GA)
- Group II (QL)Treatment being tested
Patients in Group II (QL) will undergo general anesthesia with tracheal intubation and mechanical ventilation. Analgesia regimen will include parenteral medication and anterior quadratus lumborum block as a regional component.
Treatment: ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, and General Anesthesia (GA)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- A Randomized Controlled Double-blinded Trial Evaluating the Efficacy of the Anterior Quadratus Lumborum Block as a Component of Multimodal Perioperative Analgesia for Abdominal Hysterectomies
- Record updated
- 16 December 2025