Studies p16 protein levels in colorectal cancer tissue samples
Checks p16 protein staining in colon and rectal cancer tissue samples against patient features.
Key facts
- Who runs it
- Sohag University
- Where
- Sohag, EgyptSee the site
- Trial code
- Registry title
- Clinicopathological Value of p16 Expression in Colorectal Carcinoma
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 1 May 2025
- Expected to end
- 30 Dec 2026
- Type of study
- Observational
- Treatments tested
- Immunohistochemical staining
- Record updated
- 10 July 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The study uses tissue samples from people with colorectal cancer. It looks at the p16 protein in the tumour tissue.
- Sex
- All sexes.
- Disease stage
- Colorectal cancer. No stage is given.
Main reasons for not taking part
- Tissue blocks with too little, destroyed or dead (necrotic) material
- Samples with too little clinical data
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Specimens from patients with colorectal cancer
- Tissue blocks with sufficient material
- Specimens with sufficient clinical data
Who cannot take part
- Tissue blocks with insufficient, destroyed or necrotic material
- Specimens with insufficient clinical data
Where in Egypt
- Faculty of MedicineSohag, EgyptContact: Magdy M Amin, ProfessorTaking people
About the trial
What the trial wants to find out
Evaluation of the immunohistochemical expression of p16 in colorectal carcinoma and correlate its expression to different clinical and pathological parameters as patients' ages, sexes, tumor location, histopathological phenotype, status of nodal involvement, perineural and lymphovascular invasion.
The group in the trial
- Participants
Fifty (50) cases of colorectal cancer will be performed from archieved formalin-fixed, paraffin-embedded tissue blocks referred to Pathology Department, Sohag University Hospitals.
Treatment: Immunohistochemical staining
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Clinicopathological Value of p16 Expression in Colorectal Carcinoma: An Immunohistochemical Study.
- Plain-language title
- Studies p16 protein levels in colorectal cancer tissue samplesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 10 July 2025