Tests Rocklatan eye drops after minimally invasive glaucoma surgery
Tests whether Rocklatan eye drops lower eye pressure after surgery in adults with glaucoma.
Plain-language title generated from the registry record
Registry title: Rocklatan Adds Pressure Reduction After MIGS (Minimally Invasive Glaucoma Surgery)
Key facts
- Where
- Las Vegas, United StatesSee the site
- Phase
- Phase 4
Where in United States
- Center for SightLas Vegas, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Center for Sight Las Vegas
- Trial code
- NCT07048886
- Record updated
- 3 July 2025
- Original description
The primary objective of this study is to determine if the addition of Rocklatan post-Hydrus will provide additional intraocular pressure lowering.Read full original descriptionShow less
Rocklatan Adds Pressure Reduction After MIGS (Minimally Invasive Glaucoma Surgery)
The primary objective of this study is to determine if the addition of Rocklatan post-Hydrus will provide additional intraocular pressure lowering.
Inclusion: Age 40 years and older; Subjects who have mild to moderate Open Angle Glaucoma (OAG); Subjects who have undergone uncomplicated cataract surgery and Hydrus microstent implantation > 3 months prior to screening and within the last 2 years; Post-Hydrus subjects on 0-2 ocular hypotensive medication classes who can safely washout (if on ocular hypotensive medications); Unmedicated or washed out IOP range between 16-26 mmHg.
Exclusion: Prior Selective Laser Trabeculoplasty (SLT) within 18 months of surgery; Anticipated use of intra-ocular or topical steroids not associated with the study protocol; History of intraocular surgery except for uneventful refractive surgery or uncomplicated cataract surgery and hydrus microstent implantation; Secondary glaucoma excluding pseudoexfoliation and pigmentary dispersion syndrome; Allergy or intolerance to Rocklatan; History of corneal edema, or corneal disease or dystrophy; Current or history of intra-ocular infection or inflammation; History of retinal diseases that could affect diagnostic testing; Any condition in the opinion in the investigator that would potentially confound the results of the study; Severe Open Angle Glaucoma; Narrow angles, other angle abnormalities or angle closure glaucoma; Pregnant, breastfeeding or planning to become pregnant during the study.