Microbiome and Atopy in Mali
Key facts
- Where
- Bamako, MaliSee the 2 sites
Where in Mali
- Dermatology Hospital of BamakoBamako, MaliTaking people
- Pneumology Ward, Point G University HospitalBamako, MaliTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Institute of Allergy and Infectious Diseases (NIAID)
- Trial code
- NCT07051902
- Record updated
- 15 April 2026
- Original description
This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes. In this study, the investigators will look for clues about things that may affect whether people get allergic diseases. The investigators will look at things on or in the body, like germs, and things in the environment, like pollution. To do this, the investigators will collect different types of biological samples, health information, and environmental information from people with allergic diseases and people without allergic diseases. The investigators will compare what is found in each group to look for differences that might be related to allergic disease.Read full original descriptionShow less
Analyzing the Microbiome and Environmental Exposures of Patients Suffering From Atopic Diseases in Mali
This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes. In this study, the investigators will look for clues about things that may affect whether people get allergic diseases. The investigators will look at things on or in the body, like germs, and things in the environment, like pollution. To do this, the investigators will collect different types of biological samples, health information, and environmental information from people with allergic diseases and people without allergic diseases. The investigators will compare what is found in each group to look for differences that might be related to allergic disease.
Inclusion: Aged ≥3 years; Able to provide informed consent (for ages ≥18 years) or has a parent or guardian who can provide informed consent on their behalf (for ages <18 years); Positive Screening questionnaire for asthma or eczema; Diagnosed with atopic dermatitis or asthma via physician diagnosis and criteria as follows:; Clinical diagnosis of atopic disease, as defined by Hanifin and Rajka criteria, that has been present for ≥3 months before the screening visit; Aged ≥3 years; Able to provide informed consent (for ages ≥18 years) or has a parent or guardian who can provide informed consent on their behalf (for ages <18 years); Negative Screening questionnaire for asthma and eczema; In good general health as evidenced by medical history and not diagnosed with atopic dermatitis or asthma via physician diagnosis; Failure to meet Hanifin and Rajka criteria and <3 on GINA guidelines for asthma diagnosis; No self-reported history of food allergy.
Exclusion: Use of antibiotics in the 3 months prior to screening; Treatment with an investigational drug within 12 months prior to screening; Current smoker or tobacco use within 4 months prior to screening; Current skin infections other than atopic dermatitis (e.g., scabies); Presence of current bacterial, viral, or fungal infection, with the exception of isolated onchomycosis, which is not exclusionary; Any other condition or factor that the investigator determines may significantly influence the results of testing; Current pregnancy or lactation (determined by self-report); Active diarrhea as defined by three or more loose stools per day (Bristol stool scale score of 6 or 7).