Observes Wegovy use in obesity during everyday medical care
Follows adults with obesity who take Wegovy as prescribed by their doctor.
Plain-language title generated from the registry record
Registry title: A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical Practice
Key facts
- Where
- Bern, Geneva, Lucerne, Lugano, Neuchâtel, Olten, Sankt Gallen, and Zurich, SwitzerlandSee the 9 sites
Where in Switzerland
- Praxis Dr. Schäfer, BernBern, SwitzerlandNo longer taking part
- Hôpitaux Universitaires de Genève (HUG)Geneva, SwitzerlandNo longer taking part
- Luzerner KantonsspitalLucerne, SwitzerlandNo longer taking part
- Clinica MoncuccoLugano, SwitzerlandNo longer taking part
- Centre médical de l'obésité et du diabèteNeuchâtel, SwitzerlandNo longer taking part
- Kantonsspital OltenOlten, SwitzerlandNo longer taking part
- Praxis Prof. Dr. med. G. RudofskyOlten, SwitzerlandNo longer taking part
- Stoffwechselzentrum St. GallenSankt Gallen, SwitzerlandNo longer taking part
- Universitätsspital ZürichZurich, SwitzerlandNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Novo Nordisk A/S
- Trial code
- NCT07055607
- Record updated
- 4 August 2026
- Original description
This observational study will explore how Wegovy® (Semaglutide) is used in everyday situations, how it might affect things like weight, body mass index (BMI) and waist circumference, and what kind of impact it could have on overall quality of life. The overall purpose of this study is to understand how Wegovy impacts weight when used as part of regular medical care. Participants will be treated with Wegovy as prescribed to the participant by their doctor, in accordance with normal clinical practice. The study will last for about two years.Read full original descriptionShow less
A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical Practice
This observational study will explore how Wegovy® (Semaglutide) is used in everyday situations, how it might affect things like weight, body mass index (BMI) and waist circumference, and what kind of impact it could have on overall quality of life. The overall purpose of this study is to understand how Wegovy impacts weight when used as part of regular medical care. Participants will be treated with Wegovy as prescribed to the participant by their doctor, in accordance with normal clinical practice. The study will last for about two years.
Inclusion: Signed consent obtained before any study-related activities (study-related activities are any pro-cedure related to recording of data according to the protocol); Are eligible for Wegovy and are due to initiate treatment for the first time within the study period; the decision to initiate treatment with commercially available Wegovy has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician before and independently from the decision to include the patient in this study; Male or female, age above or equal to 18 years at time of signing informed consent; Have at least one reported weight measurement documented at baseline or within 28 days prior to baseline; Participants must be able to complete the electronic patient reported outcome (ePRO) questionnaires on a compatible electronic device with internet access; Fulfil the respective reimbursement criteria in the visit prior to / at baseline in Switzerland and United Kingdom (UK).
Exclusion: Previous participation in this study. Participation is defined as having given informed consent in this study; Previous treatment with other obesity management pharmacotherapy or any glucagon like pep-tide-1 (GLP- 1) receptor agonist up to 90 days prior to baseline in Switzerland and UK; Previous treatment with other obesity management pharmacotherapy or any GLP- 1 receptor agonist up to 30 days prior to baseline in Spain; Participant has had a prior serious allergic reaction to semaglutide or any of the ingredients in Wegovy; Have had Saxenda reimbursed by basic mandatory health insurance for a cumulative period of more than 12 months prior to baseline in Switzerland; Personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) in Spain and UK; Documented history of diabetes mellitus type 1 and type 2 in Spain; Presence of diabetic complications and/or at risk of hypoglycaemia (with a documented history of frequent hypoglycaemia) in Spain; Presence of a documented refusal or unwillingness to participate in research; Pregnant or women of childbearing potential and not using a highly effective contraceptive method; Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation with the study requirements; Individuals who have reported plans to move out in the next 12 months to an area not serviced by their current site.