NCT07056738Enrolling by invitation
Prospective Exploratory Cohort Study on Ganglion Cell Degeneration in Retinitis Pigmentosa Patients
Longitudinal Characterization of Inner Retina Health in Low Vision Retinitis Pigmentosa Patients to Optimize Retinal Ganglion Cell-based Optogenetic Vision Restoration Therapy
Source: ClinicalTrials.gov · Last updated 9 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The aim of this study is an explorative prospective observation of retinal ganglion cell degeneration and/or inner retina degeneration in Retinitis pigmentosa patients. The rate and patterns of progression will be correlated to the outer retina layers as well as clinical and genetic data of patients. Secondary goal is to determine potential parameters for optogenetic treatment eligibility.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 130 (estimated)
- First submitted
- 29 Jun 2025
- Start date
- 1 Mar 2025
- Primary completion date
- 1 Mar 2030
- Lead sponsor
- University Medical Center Goettingen
- Diseases
- Retinitis pigmentosa
- NCT number
- NCT07056738
What you commit to
- Study type: Observational
- Planned participants: 130
- From 1 Mar 2025 to the primary completion date, 1 Mar 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- lack of capacity to consent in participation of study (unconsciousness, mental capacity, mental illness)
- presence of additional retinal diseases
Age
- age under 18 years
Other
- reduced cooperation during imaging or examination
- insufficient imaging quality due to hazy media (cornea, lense)
Who the study is looking for
- genetically diagnosed Retintis pigmentosa
- minimum age of 18 years (legal adult age in Germany)
- patient consent for study participation
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| EKFZ Else Kroener Fresenius Center for Optogenetic Therapies, University Medical Center Goettingen Coordinator of this site? Confirm its status | Göttingen | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.