Chronic Insomnia in Non-Cancer Pain Patients
Key facts
- Where
- Badalona, Barcelona, Girona, Hospitalet Del Llobregat, Lleida, Sant Joan Despí, Tarragona, and Terrassa, SpainSee the 15 sites
Where in Spain
- Hospital Universitari Germans Trias i PujolBadalona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital de la Santa Creu i Sant PauBarcelona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital del MarBarcelona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital Universitari Vall d'HebronBarcelona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Instituto de Medicina y CirugíaBarcelona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital Universitari de Girona Doctor Josep TruetaGirona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital de ViladecansHospitalet Del Llobregat, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital Universitari de BellvitgeHospitalet Del Llobregat, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Centre Avantmèdic PonentLleida, SpainContact: Mercè Matute, MD, PhDTaking people
- Hospital Universitari Arnau de VilanovaLleida, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Complex Hospitalari Moisés BroggiSant Joan Despí, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital de Tortosa Verge de la CintaTarragona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital Universitari Joan XXIIITarragona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Hospital Universitari Sant Joan de ReusTarragona, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
- Consorci Sanitari de TerrassaTerrassa, SpainContact: Antonio Montes Pérez, MD, PhDNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Germans Trias i Pujol Hospital
- Trial code
- NCT07057232
- Record updated
- 14 July 2025
- Original description
Pain and sleep are closely linked physiological processes that support overall health and functioning. Increasing evidence shows a dynamic, bidirectional relationship: poor sleep increases pain sensitivity, while chronic pain disrupts normal sleep. Both conditions are highly prevalent and significantly impair quality of life, making them major public health concerns.Read full original descriptionShow less
Estimating the Prevalence of Chronic Insomnia in Patients With Non-cancer Chronic Pain
Pain and sleep are closely linked physiological processes that support overall health and functioning. Increasing evidence shows a dynamic, bidirectional relationship: poor sleep increases pain sensitivity, while chronic pain disrupts normal sleep. Both conditions are highly prevalent and significantly impair quality of life, making them major public health concerns.
Chronic pain, defined as pain lasting more than three months, affects around 17% of adults in Spain. Insomnia, though common, is harder to define due to its overlap with medical and psychiatric conditions. It may present as a symptom, a syndrome, or a formal sleep disorder, leading to variability in prevalence estimates.
Current diagnostic criteria, including DSM-5 and the International Classification of Sleep Disorders, Third Edition (ICSD-3), adopt the unified concept of chronic insomnia disorder, defined as persistent difficulty with sleep initiation, maintenance, or quality, despite adequate opportunity for sleep, and associated with daytime impairment.
ICSD-3 distinguishes three types of insomnia:
* Chronic insomnia disorder: symptoms ≥3 times/week for ≥3 months; * Short-term insomnia disorder: symptoms lasting less than 3 months; * Other insomnia disorder: symptoms not meeting criteria for the above.
About one-third of the general population reports insomnia symptoms. However, when both night symptoms and daytime impact are considered, the prevalence of chronic insomnia disorder is estimated at 6-10%. Women are more frequently affected, with a female-to-male ratio of about 1.4:1.
Despite this, few studies have assessed insomnia specifically in people with chronic non-cancer pain. This gap is important, as untreated insomnia may worsen pain and reduce treatment efficacy, reinforcing a vicious cycle.
This observational study (PainSomnia) aims to estimate the prevalence of chronic insomnia among adults with chronic non-cancer pain. The results will help support integrated, individualized treatment approaches that address both sleep and pain in this high-risk population.
Inclusion: Aged 18 years or older; Either biological sex; Diagnosed with chronic non-cancer pain; Receiving care in a pain unit or by a pain specialist; Able to understand and participate in the study; Who sign informed consent.
Exclusion: Deemed unable or unlikely to cooperate adequately with study procedures at the discretion of the pain specialist or investigator.