Tracking narrowing and re-narrowing of neck arteries after surgery
Follows adults having carotid artery surgery to track narrowing that returns over time.
Plain-language title generated from the registry record
Registry title: Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study
Key facts
- Where
- Prague, CzechiaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07057297, who can take part
Where in Czechia
- Central Military Hospital PraguePrague, CzechiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Charles University, Czech Republic
- Trial code
- NCT07057297
- Record updated
- 9 July 2025
- Original description
This prospective, multicenter observational study aims to evaluate the incidence, timing, and characteristics of residual and recurrent (restenosis) carotid artery stenosis following carotid endarterectomy (CEA) with primary closure. Conducted across several neurosurgical centers in the Czech Republic, the study will include patients undergoing elective CEA who meet standard clinical indications.Read full original descriptionShow less
Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking Study
This prospective, multicenter observational study aims to evaluate the incidence, timing, and characteristics of residual and recurrent (restenosis) carotid artery stenosis following carotid endarterectomy (CEA) with primary closure. Conducted across several neurosurgical centers in the Czech Republic, the study will include patients undergoing elective CEA who meet standard clinical indications.
Participants will undergo preoperative CT angiography and follow-up imaging at 30 days and 1 year post-surgery. Residual stenosis is defined as ≥50% luminal narrowing detected within 30 days postoperatively, while restenosis is evaluated at later time points. The study will also assess clinical outcomes such as ischemic stroke, TIA, myocardial infarction, and mortality. The standardized surgical technique and harmonized diagnostic algorithm across all centers aim to provide robust data on the performance and durability of primary closure CEA.
Inclusion: Patients without matching any of exclusion criteria who underwent cartotid endarterectomy.
Exclusion: Previous endarterectomy or stenting; History of neck irradiation; Age ≤18 or ≥90 years; Unsuitable vascular anatomy; High perioperative risk; Contralateral cranial nerve X or XII palsy; Tandem carotid stenosis or intracranial vascular pathology (e.g., aneurysm or AVM); Absence of signed informed consent.