Preparing ovarian cancer patients for surgery with an intensive exercise and support program
Tests an intensive prehabilitation program in adults with ovarian cancer receiving chemotherapy before surgery.
Key facts
- Who runs it
- Medical University of Silesia
- Where
- Katowice, PolandSee the site
- Trial code
- Registry title
- Prehabilitation in Ovarian Cancer Patients During Chemiotherapy Before Cytoreductive Surgery.
- Status
- Enrolling by invitation
- People taking part
- 100 people, planned
- Started
- 1 Jul 2025
- Expected to end
- 1 Jul 2031
- Type of study
- Interventional, 2 groupsOne group gets no study treatment, for comparison.
- Treatments tested
- Prehabilitation. An intensive prehabilitation for NACT patients
- Record updated
- 10 July 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with confirmed ovarian cancer who cannot have surgery first and are referred for chemotherapy before surgery. It tests an intensive preparation programme before surgery.
- Age
- 18 to 80 years
- Sex
- Women only
- Disease stage
- Confirmed ovarian cancer where first-line surgery to remove the tumour is not possible (Fagotti score > 8 points).
- Earlier treatment
- Referred for chemotherapy before surgery (neoadjuvant chemotherapy). People who have primary debulking surgery cannot join.
Main reasons for not taking part
- Having primary debulking surgery
- Not giving consent to take part
- Aletti score < 4 points in interval debulking surgery
- Severe neurological or psychiatric disorders that make contact with the patient difficult
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Patients with confirmed ovarian cancer
- No possibility of performing primary debulking surgery (Fagotti score > 8 points). Referral patient for neoadjuvant chemotherapy
- Consent to participate in the study
- Age over 18 years
Who cannot take part
- Performing primary debulking surgery
- Aletti score < 4 points in interval debulking surgery
- Severe neurological/psychiatric disorders that make contact with the patient difficult
- Lack of consent to participate in the study
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Where in Poland
- Department of Gynecology, Obstetrics and Gynecological Oncology, University Clinical Center of the Medical University of SilesiaKatowice, PolandNo longer taking part
About the trial
What the trial wants to find out
Prehabilitation includes care for patients preparing for surgery. This is a modern approach aimed at increasing the patient's functional capacity before surgery and improving postoperative results. Prehabilitation includes preoperative physical activity, nutritional intervention, psychological support, cessation of stimulants and optimization of laboratory test results.
Read full original descriptionShow less
Many studies have shown a positive effect of prehabilitation on postoperative results, mainly reducing the number of postoperative complications and shortening the hospitalization time.
The assumed time of prehabilitation is 2-6 weeks, but in the case of oncology patients, the procedure should not be delayed only for the sake of prehabilitation.
Our study includes oncology patients with ovarian cancer who are referred for neoadjuvant chemotherapy before interval cytoreductive surgery. The assumption of the study is an intensive course of prehabilitation during neoadjuvant treatment, which should provide significantly better postoperative results.
The 2 groups in the trial
- Intense course of prehabilitationTreatment being tested
Patients undergoing intense prehabilitation program
Treatment: Prehabilitation. An intensive prehabilitation for NACT patients
- Standard preoperative careNo study treatment, for comparison
Patients with standard preoperative care
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- An Intense Course of Prehabilitation in Ovarian Cancer Patients During Neoadjuvant Treatment Awaiting for Interval Debulking Surgery. PREHONED - a Prospective, Randomized, Multicentre Clinical Study.
- Plain-language title
- Preparing ovarian cancer patients for surgery with an intensive exercise and support programGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07058753, who can take part
- Record updated
- 10 July 2025