Intensive task training with telerehabilitation for severe walking problems in multiple sclerosis
Tests intensive circuit training and remote follow-up in multiple sclerosis with walking problems.
Plain-language title generated from the registry record
Registry title: Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impairment: A Feasibility Study
Key facts
- Where
- Ferrara, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07058896, who can take part
Where in Italy
- Ferrara University HospitalFerrara, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital of Ferrara
- Trial code
- NCT07058896
- Record updated
- 10 July 2025
- Original description
Multiple sclerosis (MS) is a progressive neurological disorder that often leads to severe gait impairment, limiting mobility and reducing the patient's quality of life. Motor rehabilitation has shown positive effects in people with MS (PwMS), but its efficacy tends to decrease as disability severity increases. High-intensity, task-oriented circuit training based on the principles of motor learning has been proposed as a potential strategy to improve motor function in severely impaired individuals.Read full original descriptionShow less
Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impairment Via High Intensity Task Oriented Circuit Training: A Feasibility Study
Multiple sclerosis (MS) is a progressive neurological disorder that often leads to severe gait impairment, limiting mobility and reducing the patient's quality of life. Motor rehabilitation has shown positive effects in people with MS (PwMS), but its efficacy tends to decrease as disability severity increases. High-intensity, task-oriented circuit training based on the principles of motor learning has been proposed as a potential strategy to improve motor function in severely impaired individuals.
This approach combines the benefits of high-intensity training to the motor learning principles to enhance motor skills improvement and retention.
The main questions it aims to answer are:
* Can high-intensity, task oriented training in PwMS with severe gait impairment be feasible, safe and effective in enhancing motor function? * Can telerehabilitation maintain the benefits in gait and balance gained via circuit training for a six month period?
Participants will:
* Complete 12 session ( three hour each, three times a week) of high-intensity task oriented circuit training administered in a hospital setting. The training will target key motor skills such as walking, stepping, sit to stand, wheelchair, standing and bed mobillity. * Engage in 3 months of asynchronous telerehabilitation (without physiotherapist supervision), including monthly televisits.
Inclusion: Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria; Mini-Mental State Examination (MMSE) score > 24; Expanded Disability Status Scale (EDSS) score ≥ 6.5.
Exclusion: Modifications in drug treatment within the last 3 months; Presence of other psychiatric or neurological disorders; Cardiopulmonary, renal, or liver diseases; Pregnancy.