Using eye scans to count inflammation cells in anterior uveitis
Tests whether optical coherence tomography can objectively count and sort inflammatory cells in uveitis.
Key facts
- Who runs it
- Oregon Health and Science University
- Where
- Portland, United StatesSee the site
- Trial code
- Registry title
- Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
- Status
- Recruiting
- People taking part
- 125 people, planned
- Started
- 1 Sept 2024
- Expected to end
- Dec 2026
- Type of study
- Observational, 3 groups
- Record updated
- 17 July 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with active uveitis (inflammation inside the eye), people with eye floaters from posterior vitreous detachment, and people with healthy eyes. It tests OCT eye scans to count inflammation cells.
- Age
- 5 Years to 85 Years
- Sex
- All sexes can join.
- Disease stage
- Uveitis group: active inflammation inside the eye. Types include HLA-B27 or spondyloarthritis anterior uveitis, JIA chronic anterior uveitis, HSV anterior uveitis, Birdshot chorioretinitis, Behcet, sarcoidosis, other uveitis or uveitis masquerade. PVD group: floaters with posterior vitreous detachment. Healthy group: healthy eyes.
- Earlier treatment
- Healthy group: no previous eye surgery.
Main reasons for not taking part
- Unable to give informed consent
- Unable to keep the eye still for OCT scans
- Unable to come to all study visits
- Pregnancy or breastfeeding
- Healthy group: any history of uveitis or PVD
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade
- Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD)
- Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery
Who cannot take part
- Inability to give informed consent
- Inability to maintain stable fixation for OCT imaging
- Inability to commit to required visits to complete the study
- Pregnancy and breastfeeding
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 5 and 85 years old?
Where in United States
- Casey Eye Institute, Oregon Health & Science UniversityPortland, United StatesContact: Humberto Martinez, COT, MBATaking people
About the trial
What the trial wants to find out
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.
The 3 groups in the trial
- Uveitis Group
Eyes with active inflammation due to various systemic diseases
- Posterior Vitreous Detachment Group
Eyes with vitreous floaters and posterior vitreous detachment
- Healthy/Control Group
Healthy eyes with no history of uveitis, posterior vitreous detachment, or previous eye surgery
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography
- Plain-language title
- Using eye scans to count inflammation cells in anterior uveitisGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Fit questions
- Built from NCT07065747, who can take part
- Record updated
- 17 July 2025