Testing Movement Training and Devices in People With Movement Disorders and Healthy Adults
Studies how exercise and devices like virtual reality affect movement in people with neurological conditions.
Plain-language title generated from the registry record
Registry title: Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
Key facts
- Where
- Messina, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07066137, who can take part
Where in Italy
- IRCCS Centro Neurolesi Bonino PulejoMessina, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS Centro Neurolesi Bonino Pulejo
- Trial code
- NCT07066137
- Record updated
- 3 November 2026
- Original description
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.Read full original descriptionShow less
Motor Planning, Execution, and Modulation in Healthy Individuals and Patients With Movement Disorders or Neuromuscular Diseases Using Traditional Physical Activity or Advanced Devices to Enhance Motor Learning and Sensorimotor Processing
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
This study aims to evaluate the effectiveness of traditional physical activities combined with innovative interventions such as cryotherapy, ultrasound therapy, laser therapy, transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS). It will also assess the impact of proprioceptive stimuli provided by either the immersive virtual reality (CAREN), or visuo-cognitive-motor enhancement (S.V.T.A.), and music therapy.
The main questions it aims to answer are:
How do these interventions affect motor activities and their functional recovery? What are the temporal and spatial changes in activation sequences related to motor learning and maintenance? When there is a comparison group: Researchers will compare outcomes between different intervention arms (e.g., physical activity with advanced devices vs. traditional methods) to find out if the advanced interventions result in better motor control and functional recovery.
Participants will:
* Undergo various rehabilitation protocols including physical activity and advanced interventions. * Be assessed using different tool, such as fMRI, dtMRI, and NIRS to study in vivo neuroimaging and assess changes in brain function and connectivity.
Inclusion: Montreal Cognitive Assessment (MoCA) score (adjusted for age and education) equal to or greater than 20.
Exclusion: Severe medical and psychiatric disorders potentially affecting the training.