Under construction – not a live service
Sign in
Taking people in ChinaNo phase

Studies how tumor size is measured in lung cancer with cystic airspaces

Looks at how tumor size is measured in lung cancer with cystic air spaces.

Key facts

Who runs it
Central South University
Where
Changsha, ChinaSee the site
Trial code
Registry title
Staging Strategies and Their Association With Prognosis and Therapy in Lung Cancer With Cystic Airspaces
Status
Recruiting
People taking part
500 people, planned
Started
1 Jun 2025
Planned end
1 Nov 2026
Type of study
Observational, 3 groups
Record updated
4 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with non-small cell lung cancer who had lung surgery and whose chest CT scan before surgery showed an air-filled cyst inside the tumor.

Sex
All sexes can join.
Disease stage
Non-small cell lung cancer confirmed by biopsy or by examination after surgery. The tumor must contain a well-defined air-filled cystic part on the chest CT.
Earlier treatment
Must have had surgery to remove part of the lung. Cannot have had chemotherapy, radiotherapy or targeted therapy before joining.

Main reasons for not taking part

  • History of lung disease that can cause lung cysts (for example tuberculosis, fungal lung infection, bullae, emphysema, LAM or Birt-Hogg-Dubé syndrome)
  • Chemotherapy, radiotherapy or targeted therapy before joining
  • Another cancer at the same time
  • Missing or poor-quality chest CT before surgery

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Histologically confirmed non-small cell lung cancer (NSCLC), as verified by biopsy or postoperative pathological examination
  • Patients who have undergone surgical lung resection
  • Patients with complete preoperative chest CT imaging data
  • Preoperative chest CT showing a well-defined gas-containing (air-filled) cystic component within the tumor

Who cannot take part

  • Systemic anti-tumor therapies, including chemotherapy, radiotherapy, or targeted therapies (such as monoclonal antibodies, small-molecule tyrosine kinase inhibitors, among others), were administered prior to enrollment
  • Patients with concurrent other malignancies
  • History of pulmonary diseases that could produce cystic lung lesions (e.g., tuberculosis, pulmonary fungal infections, bullae, emphysema, Lymphangioleiomyomatosis [LAM], or Birt-Hogg-Dubé [BHD] syndrome)
  • Patients with missing or poor-quality preoperative chest CT imaging data

Where in China

  • The Second Xiangya Hospital of Central South UniversityChangsha, ChinaContact: Ping JiangTaking people

About the trial

What the trial wants to find out

The goal of this observational study is to determine the most accurate tumor size measurement method for T-staging and prognostic assessment in lung cancer with cystic airspaces (LCCA). The main questions it aims to answer are:

Read full original descriptionShow less

* What is the optimal T-staging approach for accurately classifying lung cancer with cystic airspaces （LCCA) and predicting patient outcomes? * How do imaging features of cystic lesions correlate with their pathological characteristics? * What is the relationship between imaging features of cystic airspace-associated lesions and patient prognosis? * Can optimizing the T-staging method improve clinical decision-making in patients with LCCA?

The 3 groups in the trial

  • group 1

    radiologic T stage based on the maximum tumor diameter including cystic components

  • group 2

    radiologic T stage based on the diameter of the solid/invasive portion only

  • group 3

    pathologic T stage derived from the resected specimen

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
T-Staging Strategies and Their Prognostic and Therapeutic Significance in Lung Cancer With Cystic Airspaces: A Retrospective Cohort Study
Plain-language title
Studies how tumor size is measured in lung cancer with cystic airspacesGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
4 September 2026