Tests brain stimulation to help leg movement after chronic stroke
Tests intermittent theta burst brain stimulation to aid leg recovery in adults with long-term stroke.
Plain-language title generated from the registry record
Registry title: Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
Key facts
- Where
- Stockholm, SwedenSee the site
Where in Sweden
- Department of Rehabilitation Medicine, Danderyd Hospital, Danderyd, Stockholm 18288Stockholm, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Danderyd Hospital
- Trial code
- NCT07073235
- Record updated
- 25 November 2025
- Original description
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke.Read full original descriptionShow less
Neuroplastic Changes and Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Upper and Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke.
It also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.
Inclusion: Age over 18; Chronic stroke (>6 months); Residual hemiparesis FAC ≥3.
Exclusion: Metal implants; Epilepsy/seizures; Severe cognitive impairment; Pregnancy; Claustrophobia (related to MRIs exams); Untreated or unstable depression/anxiety; Other disabilities prohibiting intensive physical training.