Personalized 6-month programme for frailty in older people with bladder or kidney cancer

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 65 and older with bladder or kidney cancer who are about to have surgery. It tests a 6-month personalized programme before and after surgery.

Age

65 years and older

Sex

All sexes can join

Disease stage

Bladder or kidney cancer treated with surgery; surgery must not be done yet

Earlier treatment

Surgery must not already be done. People already on a prehabilitation prescription with a private physiotherapist cannot join.

Main reasons for not taking part

• Surgery already done
• Other health problems that make physical activity unsafe, such as heart disease, lung disease or disabling joint disease
• Severe cognitive impairment that prevents understanding the study
• Deprived of liberty or under guardianship
• Already on a prehabilitation prescription with a private physiotherapist

The registry criteria, word for word

What the trial wants to find out

Bladder and kidney cancers are commonly diagnosed in older adults. Surgery remains the primary treatment modality for patients with kidney or bladder cancer. In older patients, common co-morbidities include fatigue, physical deconditioning characterized by reduced cardiorespiratory fitness and progressing sarcopenia, pain- whether disease- related or treatment-induced- and undernutrition. These factors increased the risk of post-operative complications and exacerbate patient frailty.

The 2 groups in the trial

• Control groupNo study treatment, for comparison

  The control group will consist of patients with bladder or kidney cancer receiving standard care, which includes a comprehensive assessment by an oncogeriatrician followed by surgery approximately 4 weeks later. Postoperatively, patients will be transferred to a rehabilitation center (SSR) for recovery, in line with standard clinical practice. As part of the study protocol, control group patients will undergo additional follow-up assessments alongside their usual care. These follow-ups-conducted at baseline, and at 1, 2, 3 months, and at the final endpoint-will mirror those of the intervention group. They will include patients- completed questionnaires and physical assessments conducted by an adapted physical activity teacher.

• Interventional groupTreatment being tested

  The interventional group will consist of bladder and kidney cancer patients who will follow a personalized 6-month care pathway in addition to standard care. This pathway includes: * 2 adapted physical activity (APA) sessions per week for 4 weeks prior to surgery * 2 APA sessions/ week for 4 weeks following surgery * Therapeutic education workshops tailored to individual needs, covering topics as physical activity, nutrition, treatments, fatigue, and relaxation * Referral to the department's DAPAP for a 12-week "bridge program", consisting of one APA session per week. The study will be conducted in the oncogeriatrics departments of Saint-Etienne University Hospital and Loire Private Hospital.

  Treatment: APA, Therapeutic education workshops, and DAPAP