NCT07077304Recruiting
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Source: ClinicalTrials.gov · Last updated 5 Jun 2026
Brief summary (registry, in English)
Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of the heart. ICARDs are associated with increased cardiovascular morbidity and mortality, independently of traditional risk factors, via multiple pathophysiological mechanisms. Diagnosis and prognosis are challenged by the heterogeneity of clinical presentations. Multimodality cardiovascular imaging - including cardiovascular magnetic resonance (CMR), transthoracic echocardiography, and positron emission tomography (PET) - plays a central role in detecting and characterizing inflammatory involvement, and may offer prognostic insights. Given the limited data on the diagnostic and prognostic utility of these imaging modalities in ICARDs, the EACVI-INFLAME study aims to assess the prevalence of confirmed cardiovascular involvement in patients with suspected or established ICARDs undergoing CMR and/or cardiac PET in a multicentric international cohort.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 5000 (estimated)
- First submitted
- 16 May 2025
- Start date
- 19 Nov 2025
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Lupus (SLE), Systemic sclerosis (scleroderma), Rheumatoid arthritis, ANCA-associated vasculitis
- NCT number
- NCT07077304
What you commit to
- Study type: Observational
- Planned participants: 5000
- From 19 Nov 2025 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of heart transplant
Other
- Inability to provide non-opposition
Who the study is looking for
- Age ≥ 18 years
- Ability to provide informed non-opposition
- Referred for a CMR and/or nuclear imaging exam
- AND a suspicion of one of the following ICARDs :
- Suspected Myocarditis (acute or chronic, and whatever the aetiologies)
- Suspected Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA)
- Suspected Tako-Tsubo
- Suspected Pericarditis (acute or chronic, and whatever the aetiologies)
- Suspected Connective tissue disease with cardiovascular involvement:
- Systemic sclerosis
- Systemic lupus erythematosus
- Antiphospholipid syndrome
- Idiopathic inflammatory myopathies
- Rheumatoid arthritis, spondylarthritis
- Suspected Vasculitis with cardiovascular involvement:
- Small-vessel vasculitis (ANCA…)
- Large vessel vasculitis (Behcet disease, Takayasu…)
- Suspected Inflammatory disease with cardiovascular involvement:
- Sarcoidosis
- Still disease
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assistance Publique Hôpitaux de Paris, Paris, île de France 75010 Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.