Tests vitamin D3 effects on heart nerve control in men with Parkinson's
Tests vitamin D3 capsules on heart rate control in men with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D
Key facts
- Where
- Dhaka, BangladeshSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 51 and 70 years old?
Source: NCT07084597, who can take part
Where in Bangladesh
- Bangladesh Medical UniversityDhaka, BangladeshTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Bangladesh Medical University
- Trial code
- NCT07084597
- Record updated
- 29 July 2025
- Original description
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis DRead full original descriptionShow less
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D
Main questions it aims to answer are:
1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will
a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done.
Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV
Exclusion: Patients on following drugs will be excluded-; Antioxidant vitamin supplements; Lipid lowering medications; Antihypertensive drug; Anti-arrhythmic drug; Sedatives; Patients with a history of drug abuse including alcoholism; All patients with the history of or clinical manifestation of currently suffering from following diseases \& condition will be excluded; Severe Cardiovascular disorders; Severe neurological disorders; Severe Respiratory disorders; Severe Renal insufficiency (S. Creatinine > 1.5 mg/dl, Acute or chronic kidney disease); Severe Endocrine disease; Severe Arthritis; Severe Liver diseases; Severe Neoplastic disease; Severe Psychiatric disorder; Current use of iron, zinc, calcium, magnesium and multivitamin supplementation; Already performing yoga or breathing exercise; Hypercalcemia.
IInclusion criteria:; Male patients with of Parkinson's disease diagnosed by neurologist with unilateral or bilateral involvement and mild to moderate disability according to Hoehn and Yahr (H-Y) scale (I-III); Age: 51-70 years; BMI: 18.5-24.9 kg/m2; Vitamin D3 deficient or insufficient; On Levodopa medication.