Studies heart valve leakage and irregular heartbeat in people with atrial fibrillation
Looks at valve leakage and predictors of atrial fibrillation returning after ablation, using heart ultrasounds.
Plain-language title generated from the registry record
Registry title: The Multi-center Study of Comprehensive Atrial Fibrillation Regurgitation and Recurrent Events Evaluation
Key facts
- Where
- Shenyang, ChinaSee the site
Where in China
- First Hospital of China Medical UniversityShenyang, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- First Hospital of China Medical University
- Trial code
- NCT07085650
- Record updated
- 25 July 2025
- Original description
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the clinic and can lead to valve regurgitation and a poor prognosis. At present, atrial fibrillation ablation is one of the most effective means for the recurrence of atrial fibrillation in clinical practice, but the recurrence rate is high. Therefore, it is of great significance to find the predictors of relapse after atrial fibrillation ablation for clinical precision treatment. three-dimensional transesophageal ultrasound (3D-TEE) can comprehensively evaluate the valve regurgitation, flap ring changes, atrial or auricular thrombosis in patients with atrial fibrillation. It is also a necessary examination before atrial fibrillation ablation.Read full original descriptionShow less
The Multi-center Study of Comprehensive Atrial Fibrillation Regurgitation by 3-dimensional Transoesophageal Echocardiography and Recurrent Events Evaluation
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the clinic and can lead to valve regurgitation and a poor prognosis. At present, atrial fibrillation ablation is one of the most effective means for the recurrence of atrial fibrillation in clinical practice, but the recurrence rate is high. Therefore, it is of great significance to find the predictors of relapse after atrial fibrillation ablation for clinical precision treatment. three-dimensional transesophageal ultrasound (3D-TEE) can comprehensively evaluate the valve regurgitation, flap ring changes, atrial or auricular thrombosis in patients with atrial fibrillation. It is also a necessary examination before atrial fibrillation ablation.
Therefore, this study intends to combine 3D-TEE and three-dimensional transthoracic echocardiographic (3D-TTE) examination to evaluate the cardiac structure and function of patients. To comprehensively evaluate atrial fibrillation valve regurgitation and explore the predictors of recurrence after atrial fibrillation ablation.
Inclusion: Age ≥18 years old; Patients who came to the hospital with atrial fibrillation and intended to undergo ablation.
Exclusion: Previous history of catheter ablation; - History of left atrial or left atrial appendix thrombus, new cerebral infarction and myocardial infarction (< 6 months); Congenital heart disease, valvular heart disease, dilated heart disease, hypertrophic cardiomyopathy, pacemaker implantation, artificial valve replacement; hyperthyroidism, severe liver and kidney insufficiency; Proposed cardiac pacemaker implantation; The quality of three-dimensional transesophageal images was insufficient and could not be analyzed; refuse to sign the informed consent.