Tests rhythmic auditory stimulation with arm movement training in people with schizophrenia
Tests sound-guided arm movement training in adults with schizophrenia taking antipsychotic medicines.
Plain-language title generated from the registry record
Registry title: Effects of RAS in SZ
Key facts
- Where
- Taipei, TaiwanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07086040, who can take part
Where in Taiwan
- National Taipei University of Nursing and Health SciencesTaipei, TaiwanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shu-Mei Wang
- Trial code
- NCT07086040
- Record updated
- 25 July 2025
- Original description
The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics. The purpose of this research project is to target each patient group to examine effects of rhythmic auditory stimulation (RAS) on upper-limb movements in medicated SZ patients in a 6-month follow-up period.Read full original descriptionShow less
Effects of Rhythmic Auditory Stimulation Therapy on Upper-Limb Movements, Function, and Quality of Life in Patients With Schizophrenia: Randomized Controlled Trials
The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics. The purpose of this research project is to target each patient group to examine effects of rhythmic auditory stimulation (RAS) on upper-limb movements in medicated SZ patients in a 6-month follow-up period.
The main questions of this project are:
1. Does RAS reduce severity of upper-limb bradykinesia (slow movements) and dyskinesia (repetitive and involuntary movements) after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving second-generation antipsychotics? and 2. Does RAS reduce severity of upper-limb bradykinesia and dyskinesia after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving first-generation antipsychotics?
Researchers will compare upper-limb movement training with the aid of RAS to upper-limb movement training without the aid of RAS to see if RAS works to improve upper-limb movements in SZ patients. Participants will:
1. Undergo an interview and movement tests and fill out questionnaires before and after the movement training program and at 3-month follow-up and 6-month follow-up; and 2. Receive movement training for 40 minutes per session for a total of 21 sessions.
Inclusion: A diagnosis of schizophrenia or schizoaffective disorder; Between 18 to 60 years old; Keeping the same antipsychotics and the same dosage at least 4 weeks right before joining the study; A Edinburgh Handedness Inventory score of > 60; A Montreal Cognitive Assessment score of ≥ 24; Between 18 to 60 years old; A Edinburgh Handedness Inventory score of > 60; A Montreal Cognitive Assessment score of ≥ 24.
Exclusion: Substance abuse or drug abuse; Substance abuse or drug abuse; Taking psychotropic medications; Neurological diseases or medical conditions that affect upper-limb movements and hearing; Other psychiatric diagnoses in addition to a diagnosis of schizophrenia or schizoaffective disorder; [For healthy participants]; Neurological diseases or medical conditions that affect upper-limb movements and hearing; Psychiatric diagnoses; Presence of first-degree relatives or siblings with diagnoses of psychiatric diseases.
[For SZ patients].