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Tests nurse-led telehealth support for high blood pressure in Nepal

Tests remote nurse-guided care to help adults with high blood pressure control it.

Plain-language title generated from the registry record
Registry title: A Study Protocol to Assess the Effectiveness of Nurse-Led Telehealth Intervention for Hypertension Control in Nepal

Key facts

Where
Dhulikhel, NepalSee the site

Where in Nepal

  • Kathmandu University School of Medical SciencesDhulikhel, NepalNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Kathmandu University School of Medical Sciences
Trial code
NCT07089290
Record updated
28 July 2025
Original description
Despite being the leading cause of cardiovascular diseases and premature death worldwide, hypertension control remains a largely unmet challenge for public health systems even in developed countries. Hypertension control in Nepal is challenging due to decreased awareness, limited access to the health facilities caused by geographical constraints and health care personnel shortage. Telehealth can help address these gaps and nurse-led telehealth can be a better option as nurses can provide timely follow up, track patients' progress and offer guidance on medication adherence and lifestyle changes which are crucial for hypertension control.Read full original descriptionShow less

Effectiveness of Nurse-Led Telehealth Intervention for Hypertension Control in Nepal

Despite being the leading cause of cardiovascular diseases and premature death worldwide, hypertension control remains a largely unmet challenge for public health systems even in developed countries. Hypertension control in Nepal is challenging due to decreased awareness, limited access to the health facilities caused by geographical constraints and health care personnel shortage. Telehealth can help address these gaps and nurse-led telehealth can be a better option as nurses can provide timely follow up, track patients' progress and offer guidance on medication adherence and lifestyle changes which are crucial for hypertension control.

This study aims to evaluate the effectiveness of nurse-led telehealth for hypertension control among hypertensive adults in Nepal. We will use the Intervention Mapping (IM) approach to develop a theory-based and evidenced nurse-led telehealth intervention for hypertension control. Following IM, a parallel-group 1:1 randomized control trial 353 participants in each group will be used to evaluate the effectiveness of intervention. The intervention consists of regular BP monitoring, video conferencing and virtual drug adjustment. The follow up will be done in 3 and 6 months. Explanatory Sequential mixed Method will be used to assess the acceptability, appropriateness, and feasibility of adapting nurse-led telehealth for hypertension control.

Data collection will utilize a self-constructed semi-structured questionnaire, along with validated questionnaires. The collected data will be analyzed using STATA 14, contributing valuable insights into the potential impact of nurse-led telehealth interventions on increasing hypertension control.

Inclusion: Aged 30 years and above; Blood pressure at baseline of more than 140 or 90 mm Hg on at least two separate visits or under antihypertensive medications; Willing to monitor their blood pressure and self-titrate medication; Possess a smartphone with internet access and WhatsApp/Viber at least biweekly; No cognitive deficit and able to communicate effectively to carry out study tasks; Not planning to change residence during the 6-month follow-up.

Exclusion: Had a stroke in the past 30 days or are on dialysis; Individuals with self-reported serious advanced illness such as terminal cancer; Pregnant women; Patients in hypertensive crisis (BP ≥180/120 mm Hg); Patients enrolled in other BP research during the same period.

ClinicalTrials.gov NCT07089290