Tests a suction catheter device to remove clots in acute ischemic stroke
Tests a clot-removal suction catheter in adults with acute ischemic stroke.
Plain-language title generated from the registry record
Registry title: Study Evaluating Toro 88 Super Bore Aspiration Catheter for Acute Ischemic Stroke
Key facts
- Where
- Paris, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT07089355, who can take part
Where in France
- Hopital Fondation Adolphe de RothschildParis, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Toro Neurovascular, Inc.
- Trial code
- NCT07089355
- Record updated
- 28 July 2025
- Original description
The goal of this pilot study is to evaluate the safety and efficacy of the Toro 88 Super Bore Aspiration Catheter in acute ischemic stroke patients.Read full original descriptionShow less
Open-Label, Single-Arm Study Evaluating Toro 88 Super Bore Aspiration Catheter Safety and Efficacy in Mechanical Thrombectomy for Acute Ischemic Stroke in France
The goal of this pilot study is to evaluate the safety and efficacy of the Toro 88 Super Bore Aspiration Catheter in acute ischemic stroke patients.
Inclusion: Patients aged ≥ 18 and ≤ 90 years at the time of consent; Presenting with an acute ischaemic stroke for which symptoms (or last time seen as normal) are < 24h; With occlusion of the ICA / the M1 segment of the MCA / a vertebral artery diameter ≥3.5mm / the basilar artery, defined by eTICI≤1; Requiring endovascular treatment (mechanical thrombectomy) with or without intravenous thrombolysis; For whom the experimental device is the first-line treatment; Without pre-existing disability (mRS ≤3 and 6≤ NIHSS ≤30 before stroke); Informed consent signed :; By the patient; Or consent by a family member/trusted support person if the patient's condition does not allow them to express their consent in writing (L1111-6).
Exclusion: Concomitant intracranial haemorrhage; Known coagulation disorder; Known allergy to contrast media; Persons deprived of their liberty by judicial or administrative decision, persons under psychiatric care under articles L3212-1 and L3123-1 and persons admitted to a health or social establishment for purposes other than research (L1121-6); Known platelet count <50,000/μL; INR ≥ 3.0; APTT ≥ 2 times normal; Blood glucose < 50 mg/dL or >400 mg/dL according to the last measurement taken before the procedure; Pregnant or breast-feeding women (urine or serum pregnancy test negative at inclusion); Arterial dissection; Suspicion of vasculitis; Suspected intracranial stenosis near the occlusion site; Known coagulopathy; Significant mass effect with midline shift; Suspicion or evidence of aortic dissection, septic embolus, or bacterial endocarditis; Systolic blood pressure > 185 mmHg and/or diastolic blood pressure < 110 mmHg; Occluded arteries in more than one large vascular territory (at least two of the left and right internal carotid arteries or the territory of a carotid artery and an artery of the vertebrobasilar system); Adults under legal protection (L1121-8); Participation in other interventional clinical research.