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Measuring lung filling in ventilated COPD patients using electrical impedance imaging

Observes lung filling differences between the two lungs in adults on breathing machines with COPD.

Plain-language title generated from the registry record
Registry title: Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.

Key facts

Where
Bayonne, FranceSee the site

Where in France

  • Centre Hospitalier Côte BasqueBayonne, FranceTaking people

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Trial details

Who runs it
Centre Hospitalier de la côte Basque
Trial code
NCT07090460
Record updated
1 June 2026
Original description
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring.Read full original descriptionShow less

Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.

Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring.

This study aims to measure interlungs insufflation delay under mechanical ventilation in COPD patients

Inclusion: Patients hospitalized in the ICU and who suffered moderate or severe COP (Gold 3 and 4)), with respiratory acidosis under NIV or intubated, and equipped with EIT over the age of 18.

Exclusion: Contra indications to EIT (e.g., implantable cardiac defibrillator, pacemaker, instable spinal lesions); Broncho-pleural leaks; Pregnant or breastfeeding woman; Guardianship or curatorship; Deprived of liberty; No health insurance; Impossibility to correctly position the EIT belt (e.g., dressings, chest drainage, etc.).

ClinicalTrials.gov NCT07090460