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Studies a coronary sinus reducer for heart failure with preserved ejection fraction

Studies heart flow imaging after coronary sinus reducer placement in adults with heart failure.

Plain-language title generated from the registry record
Registry title: A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

Key facts

Where
Rochester, United StatesSee the site

Where in United States

  • Mayo ClinicRochester, United StatesTaking people

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Trial details

Who runs it
Mayo Clinic
Trial code
NCT07093528
Record updated
27 February 2026
Original description
To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)Read full original descriptionShow less

CMR Substudy of Coronary Sinus Reducer for the Management of Symptomatic Heart Failure With a Preserved Ejection Fraction (HFpEF) Associated With Coronary Microvascular Dysfunction (CMD)

To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)

Inclusion: Age ≥18; Enrollment in main CS-reducer HFPEF study IRB# 25-002292.

Exclusion: Metal implants that are not suitable for MRI; Inability or unwillingness of individual to give written informed consent.

ClinicalTrials.gov NCT07093528