Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07094100, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- The First Affiliated Hospital of Xinxiang Medical College
- Trial code
- NCT07094100
- Record updated
- 4 May 2026
- Original description
The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage.Read full original descriptionShow less
Clinical Study of Cartilage Constructed by Autologous Bone Marrow Mesenchymal Stem Cells in Repairing Articular Cartilage Defects
The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage.
Inclusion: The patients' age ranges from 18 to 65 years old, and gender is not restricted; The imaging results show that the epiphyseal growth is mature; The defects or localized injuries of joint cartilage caused by trauma or other reasons; The injured area is the distal weight-bearing surface of the femoral condyle of the knee joint, with no more than 4 lesions, and there is no injury to the cruciate ligaments; The patients voluntarily sign and provide a written informed consent form and are willing to closely cooperate with the doctor's strict postoperative rehabilitation program.
Exclusion: There are numerous bad habits such as heavy smoking, drug abuse, and excessive alcohol consumption; Has undergone open knee joint surgery within the past six months; Has an allergic constitution or a history of allergic reactions to collagen; Has primary cardiovascular diseases, lung diseases, endocrine and metabolic disorders, or other serious diseases that affect their daily life, such as tumors or AIDS; Other acute or chronic diseases, for which the researchers consider surgery to be inappropriate; The patient is extremely overweight, with a body mass index greater than 35; The lower limb alignment is valgus by more than 10° and varus by more than 5°; Multiple ligament injuries; Has severe joint stiffness or fibrosis; Has mental abnormalities; Cannot or is unwilling to undergo rehabilitation training; Pregnant or lactating women, or those planning to conceive during the trial period.