Measuring MG53 Protein Levels in Women With Polycystic Ovary Syndrome
Compares a blood protein, MG53, in women with polycystic ovary syndrome and healthy women.
Plain-language title generated from the registry record
Registry title: Evaluation of MG53 (TRIM72) Levels in Women With Polycystic Ovary Syndrome: An Observational Study
Key facts
- Where
- Gaziosmanpaşa, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women with polycystic ovary syndrome (PCOS) and healthy women without PCOS. One blood sample is taken to measure a protein called MG53.
- Age
- 18 to 45 years
- Sex
- Women only
- Disease stage
- Either diagnosed with PCOS by the Rotterdam criteria, or healthy with no PCOS.
- Earlier treatment
- Women using metformin or any hormonal treatment cannot join.
Main reasons for not taking part
- Currently pregnant
- Has a chronic disease affecting the whole body
- Uses metformin or any hormonal treatment
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT07094776, who can take part
Where in Türkiye
- University of Health Sciences, Gaziosmanpaşa Training and Research HospitalGaziosmanpaşa, TürkiyeNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Havva Betül Bacak
- Trial code
- NCT07094776
- Record updated
- 6 August 2025
- Original description
Purpose of the Study:Read full original descriptionShow less
Evaluation of MG53 (TRIM72) Levels in Women With Polycystic Ovary Syndrome: An Observational Study
Purpose of the Study:
This study is being conducted to examine a protein called MG53 (also known as TRIM72) in women with polycystic ovary syndrome (PCOS). MG53 is involved in cell membrane repair and may play a role in insulin resistance, which is common in PCOS.
Study Procedures:
Women between 18 and 45 years of age will be invited to participate. The study population will include both women diagnosed with PCOS and healthy controls. A single blood sample (approximately 5 mL) will be collected from each participant. MG53 levels will be measured using an ELISA laboratory assay.
Significance of the Study:
Analysis of MG53 levels in relation to hormonal and metabolic markers may help determine whether MG53 is associated with insulin resistance and other characteristics of PCOS.
Inclusion: Female participants aged 18 to 45 years; Diagnosed with polycystic ovary syndrome (PCOS) according to Rotterdam criteria or healthy controls without PCOS; Able and willing to provide informed consent.
Exclusion: Presence of chronic systemic disease; Currently pregnant; Use of metformin or any hormonal treatment.