Tests ketamine with midazolam for seizures in children before hospital arrival
Tests ketamine added to midazolam for prolonged seizures in children aged 2 to 16.
Plain-language title generated from the registry record
Registry title: Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK)
Key facts
- Where
- Sohag, EgyptSee the site
- Phase
- Phase 2/3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 2 and 16 years old?
Source: NCT07095842, who can take part
Where in Egypt
- Department of Pediatrics at Sohag University HospitalSohag, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sohag University
- Trial code
- NCT07095842
- Record updated
- 5 August 2025
- Original description
The goal of this pragmatic, decentralized, pre-consented, event-driven, randomized controlled trial is to investigate the efficacy of add-on ketamine to second-dose midazolam for prehospital treatment of epileptic children with convulsive status epilepticus.Read full original descriptionShow less
Efficacy of Add-on Ketamine With Second-dose Midazolam for Prehospital Treatment of Epileptic Children With Status Epilepticus
The goal of this pragmatic, decentralized, pre-consented, event-driven, randomized controlled trial is to investigate the efficacy of add-on ketamine to second-dose midazolam for prehospital treatment of epileptic children with convulsive status epilepticus.
Inclusion: Age from 2 to 16 years; Established diagnosis of epilepsy of at least 1 year duration; History of at least 1 episode of convulsive status epilepticus in the preceding 12 months.
Exclusion: Failure to obtain informed consent; Known allergies or contraindications to ketamine; Known contraindications to intramuscular injection; Presence of another family member included in the same trial; Having subsequent events (only the index event will be included).