Vitamin D3 and Brain Waves in Men With Epilepsy and Low Vitamin D
Tests vitamin D3 on brain waves in men with epilepsy and low vitamin D.
Plain-language title generated from the registry record
Registry title: Effect of Vitamin D3 Supplementation on Brain Waves in Male Epileptic Patients With Hypovitaminosis D
Key facts
- Where
- Dhaka, BangladeshSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 40 years old?
Source: NCT07096414, who can take part
Where in Bangladesh
- Bangladesh Medical UniversityDhaka, BangladeshTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Bangladesh Medical University
- Trial code
- NCT07096414
- Record updated
- 31 July 2025
- Original description
This is an experimental study (interventional self-controlled trial, pretest-post test design). The goal of this clinical trial is to evaluate the effect of vitamin D3 supplementation on quantitative EEG in male epileptic patients with hypovitaminosis D.Read full original descriptionShow less
Effect of Vitamin D3 Supplementation on Brain Waves in Male Epileptic Patients With Hypovitaminosis D: A Quantitative Electroencephalogram Analysis
This is an experimental study (interventional self-controlled trial, pretest-post test design). The goal of this clinical trial is to evaluate the effect of vitamin D3 supplementation on quantitative EEG in male epileptic patients with hypovitaminosis D.
. The main question it aims to answer is:
Vitamin D3 supplementation has effect on brain waves in male epileptic patients with hypovitaminosis D.
Researcher will compare the effect of Vitamin D3 supplementation on brain waves in male epileptic patients with hypovitaminosis D with their pre-intervention (baseline) condition on brain waves to assess whether there will be any improvement of brain electrical activity by quantitative electroencephalogram (QEEG).
Participants will:
Take Vitamin D3 orally for 8 weeks (50,000IU/week) Visit the medical university after 8 weeks for evaluation of serum 25 (OH) D level and quantitative electroencephalogram (QEEG) Must bring the empty strips of Vitamin D supplement with them during their visit
Inclusion: Diagnosed male patients with Epilepsy by neurologist from the Out Patient Department of Department of Neurology, BMU by taking proper history of at least two unprovoked (or reflex) seizures occurring > 24 hours apart, from patients and eye witnesses; Hypovitaminosis D (<30 ng/ml); BMI : 20 - 24 kg/m²; On antiepileptic medication for 6 months to 2 years (enzyme inducing AEDs, e.g. Carbamazepine, Phenytoin, Phenobarbital); Without any medication that affect central nervous system other than antiepileptic drugs (Antidepressants, Antipsychotic, Anxiolytic, Anesthetic drugs); Apparently normal physical health.
Exclusion: Patients suffering from absence seizure; Known hypersensitivity to vitamin D3; Patients with hypertension; Patient with Thyroid disorder; Patient with Diabetes mellitus; Patient with Renal Disease; Patient with liver Disease; Certain AEDs (Sodium valproate, Ethosuximide, Oxcarbazepine, Topiramate, Lamotrigine, Levetiracetam); Smoker; Alcoholic; Patient with hypercalcemia.