Virtual Reality Gait Training With a Walking Brace for Multiple Sclerosis
Tests virtual reality with sensors and a walking brace to train walking in multiple sclerosis.
Plain-language title generated from the registry record
Registry title: VR and Orthoses for Rehabilitation in Multiple Sclerosis
Key facts
- Where
- Bologna, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07096700, who can take part
Where in Italy
- IRCCS Istituto delle Scienze Neurologiche di Bologna - AUSL of BolognaBologna, ItalyNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Azienda Usl di Bologna
- Trial code
- NCT07096700
- Record updated
- 30 March 2026
- Original description
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis (MS). The aim is to determine whether this approach can enhance clinical gait assessment and facilitate orthosis adaptation by replicating real-life scenarios within a safe and controlled environment. The virtual environment, accessed through a head-mounted display, will be delivered via a custom simulator incorporating standardized gait tasks embedded in everyday settings. This system is designed to minimize the artificial influence of clinical settings on walking performance, while providing clinicians with objective gait data for more comprehensive evaluation.Read full original descriptionShow less
Virtual Reality for Gait Training in Multiple Sclerosis (VIRTUE): an Interventional Feasibility Study
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis (MS). The aim is to determine whether this approach can enhance clinical gait assessment and facilitate orthosis adaptation by replicating real-life scenarios within a safe and controlled environment. The virtual environment, accessed through a head-mounted display, will be delivered via a custom simulator incorporating standardized gait tasks embedded in everyday settings. This system is designed to minimize the artificial influence of clinical settings on walking performance, while providing clinicians with objective gait data for more comprehensive evaluation.
Inclusion: Confirmed diagnosis of multiple sclerosis; Age between 18 and 65 years; Both sexes; Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS > 100); Expanded Disability Status Scale (EDSS between 3 and 6 inclusive); Berg Balance Scale (BBS ≥ 46); Indication for the use of the Exoband orthosis for gait assistance; Modified Fatigue Impact Scale (MFIS) physical subscale ≤ 20; Signed informed consent.
Exclusion: Presence of severe or current visual or auditory impairments; Relapses within the last 3 months; Presence of severe anxiety or depression; Severe spasticity patterns in the lower limbs or fixed distal tendon contractures; Presence of motion sickness symptoms induced by virtual reality (VR).