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Ultrasound to guide fluid removal in people with heart failure

Tests ultrasound to guide fluid removal in adults hospitalized with heart failure.

Plain-language title generated from the registry record
Registry title: Boston Medical Center Ultrasound Decongestion Study in Heart Failure

Key facts

Where
Boston, United StatesSee the site

Where in United States

  • Boston Medical CenterBoston, United StatesNo longer taking part

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Trial details

Who runs it
Boston Medical Center
Trial code
NCT07096726
Record updated
29 September 2026
Original description
The purpose of this study is to analyze the utility of a novel five-point ultrasound as a predictor of volume overload in diverse patients who are admitted with volume overload/congestive heart failure (CHF) exacerbation at Boston Medical Center (BMC), the largest safety-net hospital in New England. Current standard of care (SOC) involves the utilization of laboratory markers and physical exam, which is often inconsistent and equivocal. The investigators will assess will assess if ultrasound-assisted diuresis reduces recurrent episodes of volume overload/decompensated heart failure.Read full original descriptionShow less

Boston Medical Center Ultrasound Decongestion Study

The purpose of this study is to analyze the utility of a novel five-point ultrasound as a predictor of volume overload in diverse patients who are admitted with volume overload/congestive heart failure (CHF) exacerbation at Boston Medical Center (BMC), the largest safety-net hospital in New England. Current standard of care (SOC) involves the utilization of laboratory markers and physical exam, which is often inconsistent and equivocal. The investigators will assess will assess if ultrasound-assisted diuresis reduces recurrent episodes of volume overload/decompensated heart failure.

Inclusion: Patient with a primary diagnosis of acute on chronic decompensated heart failure who is admitted to inpatient or presents to the outpatient Boston Medical Center (BMC) Heart Failure Infusion clinic for decongestion treatment; Willing and able to receive short abdominal and thoracic ultrasounds throughout hospitalization; Patients with right and/or left ventricular failure.

Exclusion: Abdominal surgery in the past 1 month; Severe acute kidney injury (AKI) or requiring renal replacement therapy; Significant acute or chronic liver disease; End stage renal disease on dialysis; Acute valvular disease; Acute type 1 myocardial infarction; Medical condition precluding abdominal ultrasound due to significant discomfort or pain; Advanced chronic kidney disease (CKD) [Stage V CKD with glomerular filtration rate (GFR) <15] to exclude renal vein doppler ultrasound; Hemodynamic instability defined as systolic blood pressure <85 mmHg or mean arterial pressure <60 mm Hg for greater than 24 hours duration; Known abdominal thrombus in the inferior vena cava (IVC) or portal vein; Acute myocarditis; Adults not able to provide consent (a simple teach back method of key aspects discussed in consent form will be utilized to verify if patient is able to adequately provide informed consent).

ClinicalTrials.gov NCT07096726