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Brain stimulation with vision training for people with vision loss after brain damage

Tests brain stimulation with vision training in adults with homonymous hemianopia.

Plain-language title generated from the registry record
Registry title: Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training

Key facts

Where
Washington D.C., United StatesSee the site

Where in United States

  • Georgetown University Medical CenterWashington D.C., United StatesTaking people

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Trial details

Who runs it
Georgetown University
Trial code
NCT07105358
Record updated
14 September 2026
Original description
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.Read full original descriptionShow less

Visual Plasticity Following Brain Lesions

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

Inclusion: At least 18 years of age; Capable of providing informed consent and complying with study procedures; Unilateral or bilateral focal brain damage causing loss of vision; At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year; At least 18 years of age; Capable of providing informed consent and complying with study procedures.

Exclusion: Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5; Previous head injury; Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5; Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results; Vision loss resulting from ocular disease or disorder; Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results; Healthy volunteers (age-matched controls):.

Stroke, brain tumor, or traumatic brain injury patients.

ClinicalTrials.gov NCT07105358