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Heart ultrasound measures of the right heart after a sudden lung blood clot

Compares heart ultrasound measures of right heart function in people with acute pulmonary embolism.

Key facts

Who runs it
Assiut University
Where
Egypt1 site in 1 countryChoose a country to see its sites
Trial code
Registry title
Assessment of Right Ventricular Function After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters
Status
Not yet recruiting
People taking part
100 people, planned
Started
Sept 2025
Expected to end
Mar 2028
Type of study
Observational
Record updated
14 August 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a new, confirmed blood clot in the lungs (acute pulmonary embolism). It studies heart ultrasound measures of the right side of the heart.

Age
18 years and older
Sex
All sexes
Disease stage
Acute pulmonary embolism confirmed by CT pulmonary angiography. A heart ultrasound (echocardiography) must be done within 24 hours of diagnosis.

Main reasons for not taking part

  • Serious right heart weakness from before, for example from chronic pulmonary hypertension, cor pulmonale or congenital heart disease
  • History of coronary artery disease, or left heart pumping (ejection fraction) below 50%
  • Moderate to severe heart valve disease
  • An earlier documented pulmonary embolism
  • Unstable blood pressure or circulation, or poor ultrasound images

The registry criteria, word for word

Show all 10 criteriaShow less

Who can take part

  • Adults ≥18 years
  • Confirmed acute PE (via CT pulmonary angiography).(4,6)
  • Echocardiography performed within 24 hours of diagnosis

Who cannot take part

  • Prior document of an episode of pulmonary embolism
  • Pre-existing significant RV dysfunction (e.g., due to chronic pulmonary hypertension, cor pulmonale or congenital heart disease)
  • History of coronary artery disease
  • Moderate to severe valvular heart disease
  • Impaired LV systolic function, ejection fraction <50%
  • Poor acoustic window
  • Hemodynamic instability

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Echocardiographic Assessment:

Read full original descriptionShow less

Performed within 24h of PE diagnosis Conventional parameters: TAPSE, RV FAC, RV/LV ratio, tricuspid S', PASP STE parameters: RV free wall longitudinal strain (RVFWS), global longitudinal strain (GLS) if feasible All measurements averaged over 3 cardiac cycles (sinus) or 5 (AF)

Follow-up data:

ICU/hospital LOS Need for vasopressors/mechanical ventilation In-hospital and 30-day mortality

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Assessment of Right Ventricular Function for Diagnosis and Prognosis After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters
Plain-language title
Heart ultrasound measures of the right heart after a sudden lung blood clotGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Record updated
14 August 2025