Testing eccentric cycling exercise in adults with type 2 diabetes
Compares two intensities of eccentric cycling with conventional cycling in adults with type 2 diabetes.
Plain-language title generated from the registry record
Registry title: Long-Term Benefits of Eccentric Cycling Exercise in Patients With Type 2 Diabetes Mellitus
Key facts
- Where
- Kepala Batas, MalaysiaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 60 years old?
Source: NCT07109102, who can take part
Where in Malaysia
- Cardio and Muscle Function Laboratory, Pusat Perubatan USM BertamKepala Batas, MalaysiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universiti Sains Malaysia
- Trial code
- NCT07109102
- Record updated
- 7 August 2025
- Original description
The goal of this interventional study is to evaluate the long-term benefits of eccentric (ECC) cycling exercise on physiological responses, exercise capacity, and quality of life (QoL) in patients with type 2 diabetes mellitus (T2DM). The main questions it aims to answer are:Read full original descriptionShow less
Exploring Long-Term Benefits of Eccentric Cycling Exercise on Physiological Responses, Exercise Capacity, and Quality of Life in Patients With Type 2 Diabetes Mellitus
The goal of this interventional study is to evaluate the long-term benefits of eccentric (ECC) cycling exercise on physiological responses, exercise capacity, and quality of life (QoL) in patients with type 2 diabetes mellitus (T2DM). The main questions it aims to answer are:
* What are the effects of ECC cycling compared to concentric (CON) cycling on physiological responses, exercise capacity, and QoL in patients with T2DM? * What are the differential effects of moderate- and high-intensity ECC cycling compared to CON cycling on physiological responses, exercise capacity, and QoL in patients with T2DM?
Researchers will compare moderate- and high-intensity ECC cycling to CON cycling (conventional cycling) to see if ECC cycling can be a viable alternative or complement to existing exercise protocols for managing T2DM.
Participants will:
* Undergo pre-, mid-, and post-intervention assessment * Perform either moderate- or high-intensity ECC cycling or moderate intensity CON cycling according to group randomisation by the researcher. * Start with two familiarisation sessions prior to the actual cycling training. * Perform cycling exercise twice per week for 10 weeks.
Inclusion: Male diagnosed with T2DM; Age 30 - 60 years old; Height ≥155cm (To ensure proper ergonomics, comfort and safety during cycling); HbA1C level between 6-8%; No resistance exercise for ≤ 3 months before participating in the current study; Physical inactivity (moderate to vigorous exercise ≤60 minutes weekly based on International Physical Activity Questionnaires-Short Form (IPAQ-SF)).
Exclusion: Acute illness or any foot ulcer, diabetic ulcer, retinopathy, kidney, musculoskeletal, cardiovascular, or neurological disorder that could impair exercise performance or pose a risk to participants during exercise; Insulin injection.