Heart rhythm problems in emergency patients with a non-ST elevation heart attack
Observes how often serious heart rhythm problems occur in adults with a heart attack.
Key facts
- Who runs it
- University Hospital, Strasbourg, France
- Where
- Colmar, Haguenau, Mulhouse, Nancy, Poitiers, Pont-à-Mousson, Reims, Séléstat, Strasbourg, and Toul, FranceSee the 10 sites
- Trial code
- Registry title
- Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome
- Status
- Not yet recruiting
- People taking part
- 500 people, planned
- Started
- 1 Sept 2025
- Expected to end
- 1 Oct 2028
- Type of study
- Observational
- Record updated
- 8 August 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in the emergency department with non-ST elevation acute coronary syndrome (a type of heart attack or unstable chest pain from the heart).
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Non-ST segment elevation acute coronary syndrome, diagnosed by the latest European Society of Cardiology guidelines and the 4th Universal Definition of myocardial infarction
Main reasons for not taking part
- Patients under legal protection
- Patients with cognitive impairment
- Heart injury or symptoms caused by Takotsubo syndrome, myocarditis, pericarditis or acute heart failure
- Signs of type 2 heart attack, such as acute anemia with hemoglobin < 10 g/dL, sepsis or acute low-oxygen breathing failure
- Patients who object to taking part after receiving information
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Adult (≥ 18 years old) patient admitted to the emergency department
- Able to understand the information provided
- Diagnosis of non-ST segment elevation ACS established according to the lastest guidelines from the European Society of Cardiology and the 4th Universal Definition of myocardial infarction
- No objection to participation in the study after receiving appropriate information
Who cannot take part
- Patient with cognitive impairment
- Myocardial injury and/or symptoms attributable to Takotsubo syndrome, myocarditis, pericarditis, or acute heart failure
- Clinical evidence suggestive of type 2 myocardial infarction, including acute anemia with hemoglobin < 10 g/dL, sepsis, acute hypoxemic respiratory failure
- Patients subject to legal protection
Where in France
- Hôpital Louis PasteurColmar, FranceContact: Kasarra BEN HAMMOUDA, DrNo longer taking part
- Centre Hospitalier de HaguenauHaguenau, FranceContact: Florent BAICRY, DrNo longer taking part
- Hôpital Emilie MullerMulhouse, FranceContact: Marc NOIZET, DrNo longer taking part
- CHRU de NancyNancy, FranceContact: Tahar CHOUIHED, DrNo longer taking part
- CHU de Poitiers - La MiletriePoitiers, FranceContact: Nicolas MARJANOVIC, DrNo longer taking part
- Centre Hospitalier de Pont-à-MoussonPont-à-Mousson, FranceContact: Tahar CHOUIHED, DrNo longer taking part
- Hôpital Maison BlancheReims, FranceContact: Stéphane GENNAI, DrNo longer taking part
- Centre Hospitalier de SélestatSéléstat, FranceContact: Mathieu OBERLIN, DrNo longer taking part
- Hôpitaux Universitaires de Strasbourg (NHC)Strasbourg, FranceContact: Sabrina GARNIER-KEPKA, Dr (principal investigator)No longer taking part
- Centre Hospitalier de Toul Saint-CharlesToul, FranceContact: Tahar CHOUIHED, DrNo longer taking part
About the trial
What the trial wants to find out
Cardiovascular diseases are the leading cause of death worldwide. Among them, coronary artery disease-especially in its acute form, known as acute coronary syndrome (ACS)-is the most frequent cause of cardiovascular death. There are two main types of ACS: ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation ACS (NSTE-ACS). While the occurrence of serious heart rhythm and conduction disturbances is well established in STEMI, these complications are believed to be much less frequent in NSTE-ACS. However, their actual frequency in this population remains unclear due to limited studies, especially in emergency settings.
Read full original descriptionShow less
The main purpose of this study is to estimate the frequency of serious rhythm and conduction disorders in patients presenting with NSTE-ACS in emergency departments. The hypothesis is that these events are rare in this population and may not justify routine continuous cardiac monitoring for all such patients, as currently recommended.
Secondary objectives include identifying risk factors for these complications, estimating their frequency during hospitalization, assessing the frequency of minor rhythm and conduction disorders, evaluating care times and patient flow in emergency departments, and assessing patient outcomes up to 30 days-including hospitalizations, length of stay, discharge disposition, all-cause mortality, and the occurrence of five major adverse cardiovascular events (5-point MACE).
The group in the trial
- Non-ST segment elevation ACS
500 adult patients admitted to the emergency department and diagnosed with non-ST segment elevation ACS
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome
- Plain-language title
- Heart rhythm problems in emergency patients with a non-ST elevation heart attackGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 8 August 2025