Frontlight ResearchEarly access
Taking people in United StatesNo phase
Long-term study of CCM therapy in people with heart failure
Observes long-term safety and effects of CCM therapy in adults with heart failure.
Key facts
- Who runs it
- Impulse Dynamics
- Where
- Ann Arbor, Boston, Browns Mills, El Paso, Germantown, Hackensack, Haddon Heights, Kansas City, Londonderry, Lynchburg, Mesa, Milwaukee, Minneapolis, Newark, Novi, Oklahoma City, Orlando, Phoenix, Portland, Surprise, Tampa, Tyler, Vancouver, West Reading, and Ypsilanti, United StatesSee the 30 sites
- Trial code
- Registry title
- CCM OPEN HF Registry
- Status
- Recruiting
- People taking part
- 5,500 people, planned
- Started
- 1 Nov 2025
- Expected to end
- 1 Aug 2036
- Type of study
- Observational, 3 groups
- Record updated
- 27 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The registry is looking for adults with heart failure who have been or will be given an Impulse Dynamics CCM device. It follows how safe and how well this therapy works in everyday care.
- Age
- 18 years or older
- Sex
- Men and women can join.
- Earlier treatment
- Must have been or will be implanted with an Impulse Dynamics CCM device (for example CCM or CCM-D when available), as decided by the investigators.
Main reasons for not taking part
- Patients who do not follow the plan, for example for follow-up visits or medication, as judged by the investigators
- People with a mechanical tricuspid valve
- People who cannot or will not give informed consent, including for the use of their data for research
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Patients who have /will be implanted with Impulse Dynamics CCM technologies (e.g. CCM or CCM-D when available) as determined by investigators
- Willing and able to provide informed consent, including for use of data for research purposes (e.g. publication, sub-studies/sub-analyses)
Who cannot take part
- Noncompliant patients (e.g. for follow-up visits, medication, etc.) as determined by investigators
- Subjects with a mechanical tricuspid valve
Where in United States
- University of MichiganAnn Arbor, United StatesContact: Mamid Ghanbari, MD (principal investigator)Not yet recruiting
- Massachusetts General HospitalBoston, United StatesContact: Payton BlackTaking people
- Deborah Heart and Lung CenterBrowns Mills, United StatesContact: Lout LewisNot yet recruiting
- David Turbay, MDEl Paso, United StatesContact: Ricardo PulidoTaking people
- Texan Cardiovascular InstituteEl Paso, United StatesContact: Christy WillisNot yet recruiting
- The Stern Cardiovascular Foundation, IncGermantown, United StatesContact: Kari FondrenTaking people
- Hackensack University Medical CenterHackensack, United StatesContact: Manuel CastilloNot yet recruiting
- Heart HouseHaddon Heights, United StatesContact: Elizabeth WatsonTaking people
- Saint Luke's Hospital Mid America Heart InstituteKansas City, United StatesContact: Caroline MurrayNot yet recruiting
- Saint Luke's Hospital of Kansas CityKansas City, United StatesContact: Kendra BlackNot yet recruiting
- University of Kansas Medical CenterKansas City, United StatesContact: Quratulain MushtaqNot yet recruiting
- Cardiovascular Specialists of New England Research FoundationLondonderry, United StatesContact: Jennifer DriscollTaking people
- Centra Health, Inc. dba Stroobants Cardiovascular CenterLynchburg, United StatesContact: Cindy BaumannTaking people
- CardioVascular Associates of MesaMesa, United StatesContact: Adam Gitkin, MSTaking people
- Advocate Aurora Health-St. LukesMilwaukee, United StatesContact: Rebecca HoughNot yet recruiting
- Minneapolis Heart Institute Research FoundationMinneapolis, United StatesContact: Jilianne FeolaNot yet recruiting
- Rutgers New Jersey Medical School/University HospitalNewark, United StatesContact: Adel AlyNot yet recruiting
- Henry Ford Providence HospitalNovi, United StatesContact: Candice EdilloNot yet recruiting
- Oklahoma Heart Hospital Research FoundationOklahoma City, United StatesContact: Rebecca StrailyTaking people
- AdventHealth OrlandoOrlando, United StatesContact: Jennifer LydenNot yet recruiting
- HonorHealth Research InstitutePhoenix, United StatesContact: Kevin StoneNot yet recruiting
- University of Arizona and Banner University Medical Center PhoenixPhoenix, United StatesContact: Sydney MintalarNot yet recruiting
- Legacy Medical Group CardiologyPortland, United StatesContact: Kristin HickeyNot yet recruiting
- Providence St. Vincent Medical CenterPortland, United StatesContact: Sarah JacksonNot yet recruiting
- Peak Heart and VascularSurprise, United StatesContact: Neha JoshiTaking people
- AdventHealth TampaTampa, United StatesContact: Cynthia PaysorNot yet recruiting
- CHRISTUS Trinity Mother Frances Health SystemTyler, United StatesContact: Susan StocksTaking people
- PeaceHealth Southwest Medical CenterVancouver, United StatesContact: May E Peggy LauNot yet recruiting
- Reading HospitalWest Reading, United StatesContact: Mary AldenferNot yet recruiting
- Trinity Ann Arbor d/b/a Michigan Heart Ann ArborYpsilanti, United StatesContact: Autumn HoweNot yet recruiting
About the trial
What the trial wants to find out
The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting.
The 3 groups in the trial
- Retrospective Cohort
Prospective Cohort
- Hybrid (Retrospective-Prospective) Cohort
Patients who will receive/ have received CCM therapy with an Impulse Dynamics devices
- Prospective Cohort
Patients who will receive CCM therapy with an Impulse Dynamics devices
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- CCM Technologies OPEN HF Registry: Observational Patient EvaluatioN of CCM® Therapy for Heart Failure
- Plain-language title
- Long-term study of CCM therapy in people with heart failureGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 27 October 2026