NCT07113730Not yet recruiting
The Kinetics Profiling of Immune Reconstitution and Clinical Outcomes
Retrospective and Prospective Study on the Kinetics Profiling of Immune Reconstitution and Clinical Outcomes in CMML Following Allogeneic Hematopoietic Stem Cell Transplantation
Source: ClinicalTrials.gov · Last updated 15 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy with poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT) remains the only potentially curative treatment. Immune reconstitution (IR) is critical for improving HSCT efficacy and quality of life among survivors, yet its dynamic impact on survival and complications like chronic graft-versus-host disease (cGVHD) in CMML is poorly defined. This study aimed to investigate the dynamics of IR following HSCT in patients with CMML and evaluate its impact on post-transplant clinical outcomes.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 27 Jul 2025
- Start date
- 13 Aug 2025
- Primary completion date
- 31 Jul 2035
- Lead sponsor
- Peking University People's Hospital
- NCT number
- NCT07113730
What you commit to
- Study type: Observational
- Planned participants: 300
- From 13 Aug 2025 to the primary completion date, 31 Jul 2035
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any condition that may render follow-up data unreliable, including but not limited to severe psychiatric disorders
Other
- Patients deemed ineligible for the study by investigators
Who the study is looking for
- Patients with confirmed diagnosis of CMML following HSCT
- Patients treated at Peking University People's Hospital since January 1, 2005
Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.