Tests a probiotic spray for cat allergy symptoms in adults
Tests a probiotic home spray against a placebo spray in adults with cat allergy.
Plain-language title generated from the registry record
Registry title: A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
Key facts
- Where
- Hangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07114133, who can take part
Where in China
- Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- Trial code
- NCT07114133
- Record updated
- 11 August 2025
- Original description
Objective of this clinical trial:Read full original descriptionShow less
A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
Objective of this clinical trial:
The goal of this clinical study is to evaluate whether an environmental probiotic spray can improve symptoms in adults with cat allergy-induced allergic rhinitis (AR) and allergic asthma (AA). It will also assess the safety of the probiotic spray. The main questions it aims to answer are:
Does the environmental probiotic spray reduce the severity of nasal and asthma symptoms in participants? Are there any adverse effects observed in participants using the probiotic spray? Researchers will compare the environmental probiotic spray group to a placebo group (a look-alike spray containing no active ingredients) to determine if the probiotic spray is effective in managing allergic rhinitis and asthma symptoms.
Participants will:
Receive the environmental probiotic spray or placebo daily for 3 months Attend monthly clinic visits for checkups and assessments Undergo a final evaluation at 3 months, including symptom scoring and safety checks
Key Assessments:
Total Nasal Symptom Score (TNSS) for allergic rhinitis Asthma Control Test (ACT) score for allergic asthma
Inclusion: Age 18-70 years；; Diagnosed with cat allergy (cat dander-specific IgE level ≥ class 2: > 0.7 IU/mL) and allergic rhinitis with or without allergic asthma; Residing in the same living environment for at least 3 months (and no plans to change residence within the next 6 months); Patients receiving conventional symptomatic treatment.
Exclusion: Current or planned use of biologic therapy; Presence of other severe systemic diseases; Any other condition that, in the investigator's judgment, may pose significant risks to the participant if enrolled in the study; Residence duration < 3 months or plans to change residence within the next 6 months; Pregnancy.